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SOX2 Antikörper (N-Term)

Name: SOX2 Antikörper (N-Term)
SKU: ABIN388797
Price: 445.5 EUR
Availability: InStock

SOX2 Reaktivität: Human WB, IF, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB14026 unconjugated

Western blot analysis of SOX2 Antibody (N-term) in 293 cell line lysates (35 μg/lane).

Flow cytometric analysis of NCI- cells using SOX2 Antibody (N-term)(bottom histogram) compared to a negative control cell (top histogram).

FACS

Immunofluorescence analysis of SOX2 Antibody (N-term) (ABIN388797 and ABIN2839124) in HeLa cells.

Western blot analysis of SOX2 (arrow) using rabbit polyclonal SOX2 Antibody (N-term) (ABIN388797 and ABIN2839124).

Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with SOX2 antibody (N-term) (ABIN388797 and ABIN2839124) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

IHC (p)

5 Abbildungen

(2 Referenzen)

Produktnummer ABIN388797

Datenblatt (PDF)

Target Alle SOX2 Antikörper anzeigen

SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
Bindungsspezifität
18

16

16

16

16

15

13

12

10

10

9

8

7

4

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 89-119, N-Term
Reaktivität
208

101

69

21

13

11

11

10

8

8

7

7

7

5

3

2

1

1
Human
Wirt
165

47

2
Kaninchen
Passende Sekundärantikörper
Klonalität
163

51
Polyklonal
Konjugat
104

16

15

11

10

9

5

5

5

4

4

4

3

3

3

3

3

1

1

1

1

1

1

1
Dieser SOX2 Antikörper ist unkonjugiert
Applikation
165

109

50

46

45

40

40

28

26

25

18

15

12

6

4

4

4

3

2

1

1

1

1

1
Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie

Zf, X, C, M, Sh

Aufreinigung

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen

This SOX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-119 amino acids from the N-terminal region of human SOX2.

Klon

RB14026

Isotyp

Ig Fraction

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anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 227-317) antibody
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anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 1-140) antibody
SOX2 Reaktivität: Human WB, IHC, IF, IP Wirt: Kaninchen Polyclonal unconjugated

anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 1-317) antibody
SOX2 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 176-305) antibody
SOX2 Reaktivität: Human, Maus WB, ELISA, IHC, Coat, StM Wirt: Maus Monoclonal SOX2-1791 unconjugated

anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (N-Term) antibody
SOX2 Reaktivität: Human, Maus, Ratte, Ziege, Schwein, Rind (Kuh), Schaf, Zebrafisch (Danio rerio), Pferd, Kaninchen, Hund WB, IHC Wirt: Kaninchen Polyclonal unconjugated

anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) antibody
SOX2 Reaktivität: Human WB, ELISA, IHC, ICC Wirt: Maus Monoclonal 10F10 unconjugated

anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (Middle Region) antibody
SOX2 Reaktivität: Human, Maus, Ratte, Ziege, Rind (Kuh), Schaf, Zebrafisch (Danio rerio), Pferd, Kaninchen, Hund, Meerschweinchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated

anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 89-119) antibody
SOX2 Reaktivität: Human WB, ELISA, IHC, IF, FACS Wirt: Kaninchen Polyclonal unconjugated

anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 251-284) antibody
SOX2 Reaktivität: Human WB, IF, FACS Wirt: Kaninchen Polyclonal RB14259 unconjugated

Applikationshinweise

IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit

6 months
Schouten, Fratantoni, Hubens, Piersma, Pham, Bielefeld, Voskuyl, Lucassen, Jimenez, Fitzsimons: "MicroRNA-124 and -137 cooperativity controls caspase-3 activity through BCL2L13 in hippocampal neural stem cells." in: Scientific reports, Vol. 5, pp. 12448, (2015) (PubMed).

Su, Qi: "Inhibition of excessive mitochondrial fission reduced aberrant autophagy and neuronal damage caused by LRRK2 G2019S mutation." in: Human molecular genetics, Vol. 22, Issue 22, pp. 4545-61, (2013) (PubMed).
Target

SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

Andere Bezeichnung

SOX2 (SOX2 Produkte)

Hintergrund

The intronless gene for SOX2 encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in the SOX2 gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation.

Molekulargewicht

34310

Gen-ID

6657

NCBI Accession

NP_003097

UniProt

P48431

Pathways

Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis