This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This BMPR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human BMPR1B.
ALK6 antikoerper, BMPR-IB antikoerper, FecB antikoerper, alk-6 antikoerper, alk6 antikoerper, cdw293 antikoerper, alk6b antikoerper, zgc:172219 antikoerper, BMPR1B antikoerper, AI385617 antikoerper, ALK-6 antikoerper, AV355320 antikoerper, Acvrlk6 antikoerper, Alk6 antikoerper, BMPR-1B antikoerper, CFK-43a antikoerper, SKR6 antikoerper, BR1b antikoerper, alk6tr antikoerper, bmpr1b antikoerper, zALK-6 antikoerper, zgc:92220 antikoerper, CDw293 antikoerper, BMP15 antikoerper, BMPRIB antikoerper, RPK-1 antikoerper, bone morphogenetic protein receptor type 1B antikoerper, bone morphogenetic protein receptor, type IBb antikoerper, bone morphogenetic protein receptor, type 1B antikoerper, bone morphogenetic protein receptor, type IBa antikoerper, BMPR1B antikoerper, bmpr1b antikoerper, bmpr1bb antikoerper, Bmpr1b antikoerper, bmpr1ba antikoerper
Hintergrund
The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.