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ATG3 Antikörper (N-Term)

ATG3 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB7456 unconjugated
Produktnummer ABIN388486
  • Target Alle ATG3 Antikörper anzeigen
    ATG3 (ATG3 Autophagy Related 3 (ATG3))
    Bindungsspezifität
    • 22
    • 15
    • 14
    • 11
    • 6
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2-31, N-Term
    Reaktivität
    • 115
    • 42
    • 42
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 117
    • 11
    • 3
    Kaninchen
    Klonalität
    • 110
    • 21
    Polyklonal
    Konjugat
    • 44
    • 12
    • 12
    • 10
    • 7
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ATG3 Antikörper ist unkonjugiert
    Applikation
    • 88
    • 55
    • 26
    • 26
    • 19
    • 18
    • 15
    • 14
    • 14
    • 8
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Homologie
    B, M, Rat, X
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This ATG3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2-31 amino acids from the N-terminal region of human ATG3.
    Klon
    RB7456
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product ATG3 Primärantikörper
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    ATG3 (ATG3 Autophagy Related 3 (ATG3))
    Andere Bezeichnung
    ATG3 (ATG3 Produkte)
    Synonyme
    atg3 antikoerper, im:6910145 antikoerper, wu:fb15g12 antikoerper, zgc:64156 antikoerper, APG3 antikoerper, APG3-LIKE antikoerper, APG3L antikoerper, PC3-96 antikoerper, 2610016C12Rik antikoerper, Apg3l antikoerper, Atg3l antikoerper, PIG-1 antikoerper, Pig1 antikoerper, ATATG3 antikoerper, K11J9.1 antikoerper, K11J9_1 antikoerper, autophagy related 3 antikoerper, autophagy 3 (APG3) antikoerper, similar to S. cerevisiae ATG3 (YNR007C) part of ubiquitin-like system that mediates Atg8-phosphatidylethanolamine conjugation required for protein-vacuolar targeting and autophagy antikoerper, atg3 antikoerper, ATG3 antikoerper, Atg3 antikoerper
    Hintergrund
    Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG3L is an E2-like conjugating enzyme facilitating covalent binding of APG8 (MAP1LC3) to phosphatidylethanolamine (PE). APG7 (an E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with APG3. Formation of the PE conjugate is essential for autophagy.
    Molekulargewicht
    35864
    Gen-ID
    64422
    NCBI Accession
    NP_001265641, NP_071933
    UniProt
    Q9NT62
    Pathways
    Autophagie
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