BAK1 Antikörper (AA 56-91)
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- Target Alle BAK1 Antikörper anzeigen
- BAK1 (BCL2-Antagonist/killer 1 (BAK1))
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Bindungsspezifität
- AA 56-91
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser BAK1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This Bak antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-91 amino acids from human Bak.
- Klon
- RB04682
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product BAK1 Primärantikörper
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- Applikationshinweise
- WB: 1:2000. IHC-P: 1:50~100
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Haltbarkeit
- 6 months
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- Target
- BAK1 (BCL2-Antagonist/killer 1 (BAK1))
- Andere Bezeichnung
- Bak (BAK1 Produkte)
- Synonyme
- BAK antikoerper, BAK-LIKE antikoerper, BCL2L7 antikoerper, CDN1 antikoerper, Bak antikoerper, N-BAK1 antikoerper, N-Bak antikoerper, Bak1 antikoerper, bak antikoerper, bak1 antikoerper, BCL2 antagonist/killer 1 antikoerper, BCL2-antagonist/killer 1 antikoerper, BCL2 antagonist/killer 1 L homeolog antikoerper, BAK1 antikoerper, Bak1 antikoerper, bak1.L antikoerper
- Hintergrund
- BAK belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. BAK localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.
- Molekulargewicht
- 23409
- Gen-ID
- 578
- NCBI Accession
- NP_001179
- UniProt
- Q16611
- Pathways
- Apoptose, Steroid Hormone Mediated Signaling Pathway, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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