This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This SENP8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 4-35 amino acids from the N-terminal region of human SENP8.
den1 antikoerper, nedp1 antikoerper, prsc2 antikoerper, MGC84956 antikoerper, F15L12.8 antikoerper, F15L12_8 antikoerper, 9130010J17Rik antikoerper, AU020827 antikoerper, Den1 antikoerper, Nedp1 antikoerper, Prsc2 antikoerper, DEN1 antikoerper, NEDP1 antikoerper, PRSC2 antikoerper, SUMO/sentrin peptidase family member, NEDD8 specific L homeolog antikoerper, Cysteine proteinases superfamily protein antikoerper, SUMO/sentrin specific peptidase 8 antikoerper, SUMO/sentrin peptidase family member, NEDD8 specific antikoerper, senp8.L antikoerper, AT5G60190 antikoerper, Senp8 antikoerper, SENP8 antikoerper
Hintergrund
NEDD8 is a ubiquitin-like protein that becomes conjugated to the cullin subunit of several ubiquitin ligases. This conjugation, called neddylation, is required for optimal ubiquitin ligase activity. SENP8 is a protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as cullins or p53.