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NEDD8 Antikörper (N-Term)
NEDD8
Reaktivität: Human
WB, IHC (p)
Wirt: Kaninchen
Polyclonal
RB0639
unconjugated
Produktdetails anti-NEDD8 Antikörper
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Target
Alle NEDD8 Antikörper anzeigen
NEDD8
(Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8))
Bindungsspezifität
Alle Epitope für NEDD8 Antikörper
AA 1-32, N-Term
Reaktivität
Alle Reaktivitäten für NEDD8 Antikörper
Human
Wirt
Alle Wirte für NEDD8 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für NEDD8 Antikörper
Polyklonal
Konjugat
Alle Konjugate für NEDD8 Antikörper
Dieser NEDD8 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für NEDD8 Antikörper
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Homologie
B, M, Rb, Rat
Aufreinigung
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This NEDD8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-32 amino acids from the N-terminal region of human NEDD8.
Klon
RB0639
Isotyp
Ig Fraction
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Alternativen
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anti-Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) (N-Term) antibody
NEDD8
Reaktivität: Human, Maus, Ratte, Affe, Rind (Kuh), Xenopus laevis
WB, IHC, IF, IHC (p), FACS, IP
Wirt: Kaninchen
Polyclonal
unconjugated
Anwendungsinformationen
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Applikationshinweise
WB: 1:1000. IHC-P: 1:50~100
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Haltbarkeit
6 months
Details zu NEDD8
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Target
NEDD8
(Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8))
Andere Bezeichnung
NEDD8 (NEDD8 Produkte )
Synonyme
NEDD-8 antikoerper, Rub1 antikoerper, CG10679 antikoerper, Dmel\\CG10679 antikoerper, NEDD8 antikoerper, dNEDD8 antikoerper, nedd8 antikoerper, ubiquitin antikoerper, si:zc14a17.5 antikoerper, GB17785 antikoerper, DDBDRAFT_0218116 antikoerper, DDBDRAFT_0238041 antikoerper, DDB_0218116 antikoerper, DDB_0238041 antikoerper, nedd8.S antikoerper, neural precursor cell expressed, developmentally down-regulated 8 antikoerper, neural precursor cell expressed, developmentally down-regulated gene 8 antikoerper, CG10679 gene product from transcript CG10679-RB antikoerper, Nedd8 antikoerper, ubiquitin-like protein Nedd8 antikoerper, neural precursor cell expressed, developmentally down-regulated 8 L homeolog antikoerper, NEDD8 antikoerper, Nedd8 antikoerper, nedd8 antikoerper, nedd8.L antikoerper
Hintergrund
NEDD8 is a ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.
Molekulargewicht
9072
Gen-ID
4738
NCBI Accession
NP_006147
UniProt
Q15843
Pathways
Ubiquitin Proteasome Pathway
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