Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

SETD7 Antikörper (AA 159-189)

SETD7 Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB2763 unconjugated
Produktnummer ABIN387997
  • Target Alle SETD7 Antikörper anzeigen
    SETD7 (SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))
    Bindungsspezifität
    • 16
    • 7
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 159-189
    Reaktivität
    • 66
    • 18
    • 10
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    Human, Maus
    Wirt
    • 55
    • 10
    • 1
    Kaninchen
    Klonalität
    • 52
    • 13
    • 1
    Polyklonal
    Konjugat
    • 33
    • 5
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SETD7 Antikörper ist unkonjugiert
    Applikation
    • 57
    • 29
    • 25
    • 17
    • 13
    • 13
    • 12
    • 10
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This SET7 (SET9) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 159-189 amino acids from the Central region of human SET7 (SET9).
    Klon
    RB2763
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product SETD7 Primärantikörper
  • Applikationshinweise
    WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    SETD7 (SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))
    Andere Bezeichnung
    SET7 (SET9) (SETD7 Produkte)
    Synonyme
    KMT7 antikoerper, SET7 antikoerper, SET7/9 antikoerper, SET9 antikoerper, set7 antikoerper, zgc:101860 antikoerper, zgc:92330 antikoerper, 1600028F23Rik antikoerper, H3K4MT antikoerper, Set7 antikoerper, Set7/9 antikoerper, mKIAA1717 antikoerper, SET domain containing lysine methyltransferase 7 antikoerper, SET domain containing (lysine methyltransferase) 7 antikoerper, SETD7 antikoerper, setd7 antikoerper, Setd7 antikoerper
    Hintergrund
    Similar to acetylation and phosphorylation, histone methylation at the N-terminal tail has emerged as an important role in regulating chromatin dynamics and gene activity. Histone methylation occurs on arginine and lysine residues and is catalyzed by two families of proteins, the protein arginine methyltransferase family and the SET-domain-containing methyltransferase family. Five members have been identified in the arginine methyltransferase family. About 27 are grouped into the SET-domain family, and another 17 make up the PR domain family that is related to the SET domain family. The retinoblastoma protein-interacting zinc finger geneRIZ1 is a tumor suppressor gene and a FOUNDING member of the PR domain family. RIZ1 inactivation is commonly found in many types of human cancers and occurs through loss of mRNA expression, frame shift mutation, chromosomal deletion, and missense mutation. RIZ1 is also a tumor susceptibility gene in mice. The loss of RIZ1 mRNA in human cancers was shown to associate with DNA methylation of its promoter CpG island. Methylation of the RIZ1 promoter strongly correlated with lost or decreased RIZ1 mRNA expression in breast, liver, colon, and lung cancer cell lines as well as in liver cancer tissues.
    Molekulargewicht
    40721
    Gen-ID
    80854
    NCBI Accession
    NP_085151
    UniProt
    Q8WTS6
Sie sind hier:
Kundenservice