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SETD8 Antikörper (N-Term)

SETD8 Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB1415 unconjugated
Produktnummer ABIN387992
  • Target Alle SETD8 Antikörper anzeigen
    SETD8 (SET Domain Containing (Lysine Methyltransferase) 8 (SETD8))
    Bindungsspezifität
    • 21
    • 8
    • 7
    • 6
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    AA 25-53, N-Term
    Reaktivität
    • 63
    • 21
    • 11
    Human, Maus
    Wirt
    • 47
    • 16
    Kaninchen
    Klonalität
    • 46
    • 17
    Polyklonal
    Konjugat
    • 27
    • 8
    • 6
    • 6
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SETD8 Antikörper ist unkonjugiert
    Applikation
    • 50
    • 36
    • 23
    • 9
    • 7
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This SET07 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-53 amino acids from the N-terminal region of human SET07.
    Klon
    RB1415
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product SETD8 Primärantikörper
  • Applikationshinweise
    WB: 1:1000. IHC-P: 1:50~100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    SETD8 (SET Domain Containing (Lysine Methyltransferase) 8 (SETD8))
    Andere Bezeichnung
    SET07 (SETD8 Produkte)
    Synonyme
    KMT5A antikoerper, PR-Set7 antikoerper, SET07 antikoerper, SET8 antikoerper, 2410195B05Rik antikoerper, AA617402 antikoerper, AW536475 antikoerper, PR-SET7 antikoerper, setd8b antikoerper, wu:fc23f12 antikoerper, zgc:171649 antikoerper, Pr-set7 antikoerper, RGD1305893 antikoerper, Setd8 antikoerper, kmt5a antikoerper, kmt5a-a antikoerper, setd8 antikoerper, setd8-a antikoerper, set8a antikoerper, setd8a antikoerper, wu:fj33f02 antikoerper, zgc:153719 antikoerper, lysine methyltransferase 5A antikoerper, lysine methyltransferase 5Ab antikoerper, lysine methyltransferase 5A S homeolog antikoerper, lysine methyltransferase 5Aa antikoerper, KMT5A antikoerper, Kmt5a antikoerper, kmt5ab antikoerper, kmt5a.S antikoerper, kmt5aa antikoerper
    Hintergrund
    SET07 is a histone methyltransferase that methylates Lys-20 of histone H4. H4 Lys-20 methylation represents a specific tag for epigenetic transcriptional repression. The nuclear SET07 protein, which associates with silent chromatin on euchromatic arms but shows no association with constitutive heterochromatin, prefers nucleosomes as substrate compared to free histones. It appears that SET07 may play a role in maintaining silent chromatin by preventing neighboring acetylation of H4 tail. Although the SET domain contains the active site of enzymatic activity, both sequences upstream and downstream of the SET domain are required for methyltransferase activity.
    Molekulargewicht
    42890
    Gen-ID
    387893
    NCBI Accession
    NP_065115
    UniProt
    Q9NQR1
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