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HDAC9 Antikörper (N-Term)

HDAC9 Reaktivität: Human WB, IF, IP, IHC (p) Wirt: Kaninchen Polyclonal RB2582 unconjugated
Produktnummer ABIN387960
  • Target Alle HDAC9 Antikörper anzeigen
    HDAC9 (Histone Deacetylase 9 (HDAC9))
    Bindungsspezifität
    • 18
    • 9
    • 8
    • 7
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2-32, N-Term
    Reaktivität
    • 89
    • 27
    • 18
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 80
    • 9
    Kaninchen
    Klonalität
    • 72
    • 17
    Polyklonal
    Konjugat
    • 44
    • 8
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    Dieser HDAC9 Antikörper ist unkonjugiert
    Applikation
    • 62
    • 47
    • 44
    • 31
    • 25
    • 9
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    C, M
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This HDAC9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2-32 amino acids from the N-terminal region of human HDAC9.
    Klon
    RB2582
    Isotyp
    Ig Fraction
  • Applikationshinweise
    IF: 1:1,000. IP: 1:100. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Salian-Mehta, Xu, McKinsey, Tobet, Wierman: "Novel Interaction of Class IIb Histone Deacetylase 6 (HDAC6) with Class IIa HDAC9 Controls Gonadotropin Releasing Hormone (GnRH) Neuronal Cell Survival and Movement." in: The Journal of biological chemistry, Vol. 290, Issue 22, pp. 14045-56, (2015) (PubMed).

    Sugo, Oshiro, Takemura, Kobayashi, Kohno, Uesaka, Song, Yamamoto: "Nucleocytoplasmic translocation of HDAC9 regulates gene expression and dendritic growth in developing cortical neurons." in: The European journal of neuroscience, Vol. 31, Issue 9, pp. 1521-32, (2010) (PubMed).

    Deng, Ewton, Mercer, Friedman: "Mirk/dyrk1B decreases the nuclear accumulation of class II histone deacetylases during skeletal muscle differentiation." in: The Journal of biological chemistry, Vol. 280, Issue 6, pp. 4894-905, (2005) (PubMed).

  • Target
    HDAC9 (Histone Deacetylase 9 (HDAC9))
    Andere Bezeichnung
    HDAC9 (HDAC9 Produkte)
    Synonyme
    HD7 antikoerper, HD7b antikoerper, HD9 antikoerper, HDAC antikoerper, HDAC7 antikoerper, HDAC7B antikoerper, HDAC9B antikoerper, HDAC9FL antikoerper, HDRP antikoerper, MITR antikoerper, AV022454 antikoerper, D030072B18Rik antikoerper, HD7B antikoerper, Hdac7b antikoerper, Mitr antikoerper, mKIAA0744 antikoerper, hdac9 antikoerper, zgc:73392 antikoerper, TWIST antikoerper, HDAC9 antikoerper, DKFZp459E171 antikoerper, HDA09 antikoerper, HISTONE DEACETYLASE antikoerper, histone deacetylase 9 antikoerper, RGD1310748 antikoerper, RGD1563092 antikoerper, hdac9-A antikoerper, histone deacetylase 9 antikoerper, histone deacetylase 9b antikoerper, histone deacetylase 9 S homeolog antikoerper, HDAC9 antikoerper, Hdac9 antikoerper, hdac9b antikoerper, HDA9 antikoerper, hdac9.S antikoerper
    Hintergrund
    Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to the Xenopus and mouse MITR genes. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. This encoded protein may play a role in hematopoiesis. Multiple alternatively spliced transcripts have been described for this gene but the full-length nature of some of them has not been determined.
    Molekulargewicht
    111297
    Gen-ID
    9734
    NCBI Accession
    NP_001191073, NP_001191074, NP_001191075, NP_001191076, NP_001191077, NP_055522, NP_478056, NP_848510, NP_848512
    UniProt
    Q9UKV0
    Pathways
    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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