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UBA2 Antikörper (C-Term)

UBA2 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB2822 unconjugated
Produktnummer ABIN387913
  • Target Alle UBA2 Antikörper anzeigen
    UBA2 (SUMO1 Activating Enzyme Subunit 2 (UBA2))
    Bindungsspezifität
    • 11
    • 7
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 601-631, C-Term
    Reaktivität
    • 50
    • 16
    • 12
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 47
    • 3
    • 1
    Kaninchen
    Klonalität
    • 41
    • 10
    Polyklonal
    Konjugat
    • 27
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser UBA2 Antikörper ist unkonjugiert
    Applikation
    • 37
    • 22
    • 20
    • 12
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This SAE2 (UBA2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 601-631 amino acids from the C-terminal region of human SAE2 (UBA2).
    Klon
    RB2822
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product UBA2 Primärantikörper
  • Applikationshinweise
    WB: 1:1000. IHC-P: 1:50~100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    UBA2 (SUMO1 Activating Enzyme Subunit 2 (UBA2))
    Andere Bezeichnung
    SAE2 (UBA2) (UBA2 Produkte)
    Synonyme
    ATSAE2 antikoerper, EMB2764 antikoerper, EMBRYO DEFECTIVE 2764 antikoerper, F3K23.23 antikoerper, F3K23_23 antikoerper, SUMO-ACTIVATING ENZYME 2 antikoerper, SUMO-activating enzyme 2 antikoerper, ARX antikoerper, SAE2 antikoerper, AA986091 antikoerper, Arx antikoerper, Sae2 antikoerper, UBA1 antikoerper, Ubl1a2 antikoerper, Uble1b antikoerper, sae2 antikoerper, sae2-B antikoerper, uba2-a antikoerper, uba2-b antikoerper, uble1b-B antikoerper, sae2b antikoerper, uble1b antikoerper, wu:fi17g06 antikoerper, zgc:66354 antikoerper, SUMO1 activating enzyme subunit 2 antikoerper, SUMO-activating enzyme 2 antikoerper, ubiquitin like modifier activating enzyme 2 antikoerper, ubiquitin-like modifier activating enzyme 2 antikoerper, ubiquitin like modifier activating enzyme 2 L homeolog antikoerper, MICPUN_63834 antikoerper, MICPUCDRAFT_36729 antikoerper, SAE2 antikoerper, UBA2 antikoerper, Uba2 antikoerper, uba2.L antikoerper, uba2 antikoerper
    Hintergrund
    Ubiquitin is covalently attached to target proteins by a multienzymatic system consisting of E1 (ubiquitin-activating), E2 (ubiquitin-conjugating), and E3 (ubiquitin-ligating) enzymes. NEDD8, a ubiquitin-like protein, is conjugated to proteins in a manner analogous to ubiquitinylation. beta-amyloid precursor protein-binding protein-1 (APPBP1) can bind to NEDD8 in rabbit reticulocyte lysates. However, since APPBP1 shows similarity to only the N-terminal domain of an E1 enzyme, it must interact with a protein showing similarity to the C-terminal region of E1s. By searching sequence databases, a cDNAs encoding UBA3 was identified as the human homolog of yeast Uba3. The predicted 442-amino acid UBA3 protein shares 43 % sequence identity with yeast Uba3. In vitro, UBA3 formed a complex with APPBP1 and a thioester linkage with NEDD8. APPBP1/UBA3 complex may function as an E1-like enzyme for the activation of NEDD8.
    Molekulargewicht
    71224
    Gen-ID
    10054
    NCBI Accession
    NP_005490
    UniProt
    Q9UBT2
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