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DNMT3A Antikörper (AA 457-486)

DNMT3A Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB15269 unconjugated
Produktnummer ABIN387882
  • Target Alle DNMT3A Antikörper anzeigen
    DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))
    Bindungsspezifität
    • 16
    • 16
    • 13
    • 12
    • 11
    • 8
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 457-486
    Reaktivität
    • 134
    • 50
    • 48
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 125
    • 12
    Kaninchen
    Klonalität
    • 115
    • 22
    Polyklonal
    Konjugat
    • 59
    • 12
    • 11
    • 11
    • 9
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser DNMT3A Antikörper ist unkonjugiert
    Applikation
    • 107
    • 68
    • 30
    • 27
    • 26
    • 21
    • 13
    • 12
    • 8
    • 6
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    C, M, Rat
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This Dnmt3a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 457-486 amino acids from the Central region of human Dnmt3a.
    Klon
    RB15269
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product DNMT3A Primärantikörper
  • Applikationshinweise
    WB: 1:1000. IHC-P: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Husni, Shiba-Ishii, Iiyama, Shiozawa, Kim, Nakagawa, Sato, Kano, Minami, Noguchi: "DNMT3a expression pattern and its prognostic value in lung adenocarcinoma." in: Lung cancer (Amsterdam, Netherlands), Vol. 97, pp. 59-65, (2017) (PubMed).

    Chestnut, Chang, Price, Lesuisse, Wong, Martin: "Epigenetic regulation of motor neuron cell death through DNA methylation." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 31, Issue 46, pp. 16619-36, (2011) (PubMed).

  • Target
    DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))
    Andere Bezeichnung
    Dnmt3a (DNMT3A Produkte)
    Synonyme
    DNMT3A antikoerper, DNMT3A2 antikoerper, M.HsaIIIA antikoerper, MmuIIIA antikoerper, dnmt3a1 antikoerper, dnmt6 antikoerper, DNA methyltransferase 3 alpha antikoerper, DNA methyltransferase 3A antikoerper, DNA (cytosine-5-)-methyltransferase 3 alpha b antikoerper, DNMT3A antikoerper, Dnmt3a antikoerper, dnmt3a antikoerper, dnmt3ab antikoerper
    Hintergrund
    CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. Dnmt3a is a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.
    Molekulargewicht
    101858
    Gen-ID
    1788
    NCBI Accession
    NP_072046, NP_715640, NP_783328, NP_783329
    UniProt
    Q9Y6K1
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