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APOA5 Antikörper (C-Term)

APOA5 Reaktivität: Human WB, EIA Wirt: Ziege Polyclonal unconjugated
Produktnummer ABIN375169
  • Target Alle APOA5 Antikörper anzeigen
    APOA5 (Apolipoprotein A-V (APOA5))
    Bindungsspezifität
    • 9
    • 7
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 52
    • 10
    • 7
    • 2
    • 1
    • 1
    Human
    Wirt
    • 42
    • 18
    • 1
    Ziege
    Klonalität
    • 44
    • 18
    Polyklonal
    Konjugat
    • 39
    • 7
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser APOA5 Antikörper ist unkonjugiert
    Applikation
    • 42
    • 23
    • 23
    • 12
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 2
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody reacts to APOA5.
    Aufreinigung
    Affinity chromatography
    Immunogen
    Peptide with sequence C-HSLHDQGHSHLGDP, from the C Terminus of the protein sequence
    Top Product
    Discover our top product APOA5 Primärantikörper
  • Applikationshinweise
    Peptide ELISA: 1/64000. Western Blot: 0.3 - 1 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0,5 mg/mL
    Buffer
    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    APOA5 (Apolipoprotein A-V (APOA5))
    Andere Bezeichnung
    Apolipoprotein A V (ApoA V) (APOA5 Produkte)
    Synonyme
    APOAV antikoerper, RAP3 antikoerper, 1300007O05Rik antikoerper, Apoav antikoerper, apo-AV antikoerper, apoA-V antikoerper, APOA5 antikoerper, MGC140487 antikoerper, rap3 antikoerper, apoav antikoerper, apoa-v antikoerper, apolipoprotein A5 antikoerper, apolipoprotein A-V antikoerper, apolipoprotein A5 L homeolog antikoerper, APOA5 antikoerper, Apoa5 antikoerper, apoa5.L antikoerper, apoa5 antikoerper
    Hintergrund
    Apolipoprotein A V is a minor apolipoprotein mainly associated with HDL and to a lesser extent with VLDL. It may also be associated with chylomicrons. It is an important determinant of plasma triglyceride (TG) levels by both being a potent stimulator of apo-CII lipoprotein lipase (LPL) TG hydrolysis and a inhibitor of the hepatic VLDL-TG production rate (without affecting the VLDL-apoB production rate). Apolipoprotein A V activates poorly lecithin:cholesterol acyltransferase (LCAT) and does not enhance efflux of cholesterol from macrophages. Apolipoprotein A V is upregulated by PPARA agonists, which are used clinically to lower serum TG (such as fibrates). It is induced in early phase of liver regeneration. Defects in Apolipoprotein A V gene are a cause of susceptibility to familial hypertriglyceridemia. It is a coronary heart disease risk factor. On a regular diet the patient demonstrates increased plasma VLDL. Plasma triglycerides are persistently increased, while plasma cholesterol and phospholipids are usually within normal limits.Synonyms: APOA5, Apo-AV, ApoA-V, Apolipoprotein A-V, RAP3, Regeneration-associated protein 3
    Gen-ID
    116519, 9606
    UniProt
    Q6Q788
    Pathways
    Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism
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