GCKR Antikörper (N-Term)

Produktnummer ABIN375154

Produktdetails anti-GCKR Antikörper

Target: GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Maus

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser GCKR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody reacts to GCKR.

Kreuzreaktivität (Details): Species reactivity (expected):Human.
Species reactivity (tested):Mouse, Rat.

Aufreinigung: Affinity chromatography

Immunogen: Peptide with sequence KRFQHVIETPEPGK -C, from the N-Terminus of the protein sequence

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/8000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu GCKR

Target: GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))

Andere Bezeichnung: GCKR (GCKR Produkte)

Synonyme: FGQTL5 antikoerper, GKRP antikoerper, GLRE antikoerper, gckr antikoerper, glucokinase regulator antikoerper, glucokinase regulatory protein antikoerper, glucokinase regulator L homeolog antikoerper, GCKR antikoerper, Gckr antikoerper, gckr.L antikoerper

Hintergrund: GCKR is a subfamily member of the SIS (Sugar ISomerase) family of proteins. It is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).Synonyms: GCKR, Glucokinase regulator, Glucokinase regulatory protein

Gen-ID: 2646, 9606

UniProt: Q14397

Pathways: Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus