Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

PAK1 Antikörper (Internal Region)

PAK1 Reaktivität: Human, Ratte, Maus, Hund WB Wirt: Ziege Polyclonal unconjugated
Produktnummer ABIN374720
  • Target Alle PAK1 Antikörper anzeigen
    PAK1 (P21-Activated Kinase 1 (PAK1))
    Bindungsspezifität
    • 34
    • 17
    • 15
    • 13
    • 10
    • 10
    • 9
    • 9
    • 8
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 174
    • 95
    • 83
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Human, Ratte, Maus, Hund
    Wirt
    • 167
    • 4
    • 1
    • 1
    Ziege
    Klonalität
    • 161
    • 13
    Polyklonal
    Konjugat
    • 91
    • 10
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    Dieser PAK1 Antikörper ist unkonjugiert
    Applikation
    • 117
    • 66
    • 45
    • 39
    • 39
    • 34
    • 32
    • 14
    • 11
    • 10
    • 10
    • 6
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB)
    Spezifität
    This antibody reacts to PAK1. No cross-reactivity exptected with PAK3.
    Kreuzreaktivität (Details)
    Species reactivity (expected):Canine.
    Species reactivity (tested):Human, Mouse, Rat.
    Aufreinigung
    Affinity chromatography
    Immunogen
    Peptide with sequence C-NTEKQKKKPKMSDE, from the internal region of the protein sequence
    Top Product
    Discover our top product PAK1 Primärantikörper
  • Applikationshinweise
    ELISA: 1/4000. Western Blot: 1 - 3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    PAK1 (P21-Activated Kinase 1 (PAK1))
    Andere Bezeichnung
    PAK1 (PAK1 Produkte)
    Synonyme
    X-PAK1 antikoerper, XPak1 antikoerper, pak antikoerper, pak-1 antikoerper, pakalpha antikoerper, PAKalpha antikoerper, AW045634 antikoerper, PAK-1 antikoerper, Paka antikoerper, p21 protein (Cdc42/Rac)-activated kinase 1 S homeolog antikoerper, p21 (RAC1) activated kinase 1 antikoerper, p21 protein (Cdc42/Rac)-activated kinase 1 antikoerper, Serine/threonine-protein kinase pak-1 antikoerper, pak1.S antikoerper, PAK1 antikoerper, Pak1 antikoerper, pak-1 antikoerper
    Hintergrund
    The serine/threonine kinase Pak1 is an effector of small Rho GTPases, Rac1 and Cdc42. Pak1 complex specifically with Rac1 and Cdc42 in their active GTP bound state, inhibiting their intrinsic GTPase activity leading to their autophosphorylation. It plays an important role in the regulation of cell morphogenesis, motility, mitosis, and angiogenesis and has been implicated in the progression of many cancers.Synonyms: Alpha-PAK, PAK 1, PAK alpha, PAK-1, Serine/threonine-protein kinase PAK 1, p21-activated kinase 1, p65-PAK
    Gen-ID
    5058
    NCBI Accession
    NP_001122092
    UniProt
    Q13153
    Pathways
    MAPK Signalweg, RTK Signalweg, T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Embryonic Body Morphogenesis
Sie sind hier:
Kundenservice