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UNC13D Antikörper (Internal Region)

UNC13D Reaktivität: Human, Maus, Ratte, Hund WB, IHC (p) Wirt: Ziege Polyclonal unconjugated
Produktnummer ABIN374716
  • Target Alle UNC13D Antikörper anzeigen
    UNC13D (Unc-13 Homolog D (UNC13D))
    Bindungsspezifität
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 25
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Hund
    Wirt
    • 21
    • 3
    • 2
    Ziege
    Klonalität
    • 24
    • 2
    Polyklonal
    Konjugat
    • 22
    • 2
    • 1
    • 1
    Dieser UNC13D Antikörper ist unkonjugiert
    Applikation
    • 21
    • 10
    • 7
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Spezifität
    This antibody reacts to Munc13-4 / UNC13D.
    Kreuzreaktivität (Details)
    Species reactivity (expected):Mouse, Rat, Canine.
    Species reactivity (tested):Human.
    Aufreinigung
    Affinity chromatography
    Immunogen
    Peptide with sequence C-ETQKHKKDLHPLFD, from the internal region of the protein sequence
    Top Product
    Discover our top product UNC13D Primärantikörper
  • Applikationshinweise
    ELISA: 1/128000. Western Blot: 1 - 3 μg/mL. Immunohistochemistry on paraffin sections: 2.5 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    UNC13D (Unc-13 Homolog D (UNC13D))
    Andere Bezeichnung
    UNC13D (UNC13D Produkte)
    Synonyme
    FHL3 antikoerper, HLH3 antikoerper, HPLH3 antikoerper, Munc13-4 antikoerper, UNC13D antikoerper, 2610108D09Rik antikoerper, Jinx antikoerper, mFLJ00067 antikoerper, Unc13h4 antikoerper, BIGH3 antikoerper, CDB1 antikoerper, CDG2 antikoerper, CDGG1 antikoerper, CSD antikoerper, CSD1 antikoerper, CSD2 antikoerper, CSD3 antikoerper, EBMD antikoerper, LCD1 antikoerper, unc-13 homolog D antikoerper, unc-13 homolog D (C. elegans) antikoerper, transforming growth factor beta induced antikoerper, UNC13D antikoerper, Unc13d antikoerper, TGFBI antikoerper, unc13d antikoerper, un13d antikoerper
    Hintergrund
    Secretion of the contents of cytolytic granules at the immunologic synapse is a highly regulated process essential for lymphocyte cytotoxicity. This process requires the rapid transfer of perforin containing lytic granules to the target cell interface, followed by their docking and fusion with the plasma membrane. Munc 13-4 localises with cytotoxic granules at the immunologic synapse. Munc 13-4 is essential for the priming step of cytolytic granule secretion preceding vesicle membrane fusion. There are two named isoforms.Synonyms: Munc13-4, Protein unc-13 homolog D
    Gen-ID
    201294, 9606
    UniProt
    Q70J99
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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