AKAP9 Antikörper (C-Term)

Produktnummer ABIN374523

Produktdetails anti-AKAP9 Antikörper

Target: AKAP9 (A Kinase (PRKA) Anchor Protein (Yotiao) 9 (AKAP9))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser AKAP9 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Spezifität: This antibody reacts to AKAP9. This antibody is expected to recognise isoforms 2 and 3. The isoforms Yotiao, AKAP350B and AKAP350C are not recognized.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography

Immunogen: Peptide with sequence C-SGSTTQFHAGMR, from the C Terminus of the protein sequence

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/32000. Western Blot: 1 - 3 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu AKAP9

Target: AKAP9 (A Kinase (PRKA) Anchor Protein (Yotiao) 9 (AKAP9))

Andere Bezeichnung: AKAP9 (AKAP9 Produkte)

Synonyme: AKAP-9 antikoerper, AKAP350 antikoerper, AKAP450 antikoerper, CG-NAP antikoerper, HYPERION antikoerper, LQT11 antikoerper, MU-RMS-40.16A antikoerper, PPP1R45 antikoerper, PRKA9 antikoerper, YOTIAO antikoerper, 5730481H23Rik antikoerper, AW545847 antikoerper, C79026 antikoerper, mKIAA0803 antikoerper, Gisp antikoerper, Yotiao antikoerper, AKAP9 antikoerper, wu:fj02h02 antikoerper, prka9 antikoerper, yotiao antikoerper, akap350 antikoerper, akap450 antikoerper, hyperion antikoerper, AKAP120 antikoerper, A-kinase anchoring protein 9 antikoerper, A kinase (PRKA) anchor protein (yotiao) 9 antikoerper, A kinase (PRKA) anchor protein 9 antikoerper, A-kinase anchoring protein AKAP120 antikoerper, AKAP9 antikoerper, Akap9 antikoerper, akap9 antikoerper, CpipJ_CPIJ006715 antikoerper, CpipJ_CPIJ017436 antikoerper

Hintergrund: AKAP9 is a novel cytoskeletal protein specifically concentrated in the neuromuscular junction and neuronal synapes that interacts with specific splice variants of NMDA Receptor Subunit NR1 in a C1 exon cassette dependent manner. It has also been shown to physically attach the type I protein phosphatase (PP1) and the adenosine 3',5'-mono-phosphate (cAMP) dependent protein kinase (PKA) holoenzyme to NMDA receptors to regulate channel activity. NMDA receptors are involved with many important functions and dysfunctions of the nervous system, including synapse formation, synaptic plasticity, and excitotoxicity. AKAP9 research may lead to a clearer understanding of these neural processes by explaining how NMDA receptors are targeted to particular synapses, how this localization is regulated during development and synaptic activity, and how NMDA receptor activity is transduced into intracellular signals responsible for particular neuronal responses.Synonyms: A-kinase anchor protein 350 kDa, A-kinase anchor protein 450 kDa, A-kinase anchor protein 9, AKAP120-like protein, AKAP350, AKAP450, KIAA0803, Protein hyperion, Protein kinase A-anchoring protein 9, Protein yotiao, entrosome- and Golgi-localized PKN-associated protein

Gen-ID: 10142, 9606

UniProt: Q99996

Pathways: M Phase, SARS-CoV-2 Protein Interaktom