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Survivin Antikörper (C-Term)

BIRC5 Reaktivität: Human WB Wirt: Ziege Polyclonal unconjugated
Produktnummer ABIN374456
  • Target Alle Survivin (BIRC5) Antikörper anzeigen
    Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))
    Bindungsspezifität
    • 20
    • 16
    • 12
    • 7
    • 7
    • 7
    • 6
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 148
    • 61
    • 51
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 113
    • 43
    • 1
    • 1
    Ziege
    Klonalität
    • 111
    • 47
    Polyklonal
    Konjugat
    • 86
    • 15
    • 10
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Survivin Antikörper ist unkonjugiert
    Applikation
    • 120
    • 55
    • 43
    • 35
    • 26
    • 24
    • 24
    • 23
    • 14
    • 13
    • 7
    • 7
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Spezifität
    This antibody reacts to Apoptosis inhibitor survivin.
    Aufreinigung
    Affinity chromatography
    Immunogen
    Peptide with sequence CVRRAIEQLAAMD, from the C Terminus of the protein sequence
    Top Product
    Discover our top product BIRC5 Primärantikörper
  • Applikationshinweise
    Peptide ELISA: 1/16000. Western blot: 0.01 - 0.5 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0,5 mg/mL
    Buffer
    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))
    Andere Bezeichnung
    IAP4 / BIRC5 (BIRC5 Produkte)
    Synonyme
    AP14 antikoerper, API4 antikoerper, EPR-1 antikoerper, AAC-11 antikoerper, Api4 antikoerper, TIAP antikoerper, survivin40 antikoerper, bir5a antikoerper, survivin antikoerper, BIR1 antikoerper, Su2 antikoerper, XBIR1 antikoerper, XSurvivin1 antikoerper, Xsvv1 antikoerper, api4 antikoerper, bir1-A antikoerper, epr-1 antikoerper, svv1 antikoerper, xSurvivin antikoerper, xsurv antikoerper, Su1 antikoerper, birc5.2 antikoerper, svv2 antikoerper, xSurvivin2 antikoerper, bir5b antikoerper, SIX antikoerper, birc5.2-a antikoerper, birc5.2-b antikoerper, baculoviral IAP repeat containing 5 antikoerper, baculoviral IAP repeat-containing 5 antikoerper, baculoviral IAP repeat containing 5a antikoerper, baculoviral IAP repeat-containing 5, gene 1 L homeolog antikoerper, baculoviral IAP repeat containing 5 L homeolog antikoerper, baculoviral IAP repeat containing 5b antikoerper, baculoviral IAP repeat containing 5 S homeolog antikoerper, BIRC5 antikoerper, Birc5 antikoerper, birc5a antikoerper, birc5.1.L antikoerper, birc5.2.L antikoerper, birc5b antikoerper, birc5.2.S antikoerper
    Hintergrund
    Survivin is an anti-apoptotic protein, expressed in the G2/M cell cycle phase. At the onset of mitosis, survivin associates with microtubules of the mitotic spindle in a specific and saturable reaction that is regulated by microtubule dynamics. Disruption of survivin-microtubule interactions results in loss of survivin's anti-apoptotic function and increased caspase 3 activity. Survivin is also abundantly expressed in brain tissues (astrocytes and some neurons) of adult rats following traumatic brain injury. Survivin has been found co-expressed with NeuN (mature neuronal marker) and PCNA (a cell cycle protein. Survivin might affect regulation of neural cell proliferative responses after brain injury. Survivin is also an inhibitor of apoptosis (IAP), or programmed cell death, that is selectively overexpressed in common human cancers.Synonyms: API4, Apoptosis inhibitor 4, Apoptosis inhibitor survivin, Baculoviral IAP repeat-containing protein 5, Survivin
    Gen-ID
    332
    NCBI Accession
    NP_001012270
    UniProt
    O15392
    Pathways
    Apoptose, Zellzyklus, Nuclear Hormone Receptor Binding
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