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beta-Catenin (CTNNB1) (C-Term) Antikörper

Antigen

beta-Catenin (CTNNB1)

Synonyme
CTNNB, FLJ25606, FLJ37923, DKFZp686D02253, Mesc, Catnb, ctnnb, id:ibd2058, wu:fb73e10, wu:fi81c06, wu:fk25h01, ARM, Beta-cat, Beta-catenin, EG:86E4.6, beta-cat-arm, l(1)2Bv, l(1)G0192, l(1)G0234, l(1) ... mehr anzeigen
Epitope
Alternativen

C-Term

Klonalität Polyklonal
Wirt
Alternativen

Kaninchen

Reaktivität
Alternativen

Human

Applikation
Alternativen Immunpräzipitation (IP), Immunhistochemie (Paraffinschnitte) (IHC (p)), Western Blot (WB)
Produktnummer ABIN373128
Menge 0.1 ml  (0.2 mg/ml)  (Varianten)
Preis 150,00 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 7 bis 10 Werktagen

Produktbeschreibung

Produktmerkmale Synonyms: CTNNB1, CTNNB, beta-1 Catenin, beta catenin, beta-Catenin 1, Catenin-beta 1
Weitere Bezeichnung Catenin beta-1
Gen-ID 1499
Swiss-Prot P35222
Immunogen A synthetic peptide from the C-terminus of the beta-Catenin protein.
Kreuzreaktivität Human, Maus
Beschreibung The catenins (alpha, beta and gamma) are ubiquitously expressed, cytoplasmic proteinsassociated with E-cadherin at cellular junctions. beta-catenin also binds to Ncadherin andco-immunoprecipitates with APC. Cadherin/catenin complexes are linked to thecytoskeleton via a direct association between alpha-actinin and alpha-catenin. Increasestyrosine phosphorylation can disrupt catenin-cadherin complexes, influencing cellularadhesion. Beta-Catenin-mediated signalling is involved at several stages of vertebrate neuraldevelopment.
Spezifität This antibody reacts to Catenin beta. Cellular Localization: Cytoplasmic and Membrane. Species Reactivity: Tested: Human. Expected from sequence similarity: Mouse. Add. Information: Molecular Weight: 92 kDa
Synonyme CTNNB, FLJ25606, FLJ37923, DKFZp686D02253, Mesc, Catnb, ctnnb, id:ibd2058, wu:fb73e10, wu:fi81c06, wu:fk25h01, ARM, Beta-cat, Beta-catenin, EG:86E4.6, beta-cat-arm, l(1)2Bv, l(1)G0192, l(1)G0234, l(1)G0410, l(1)arm, t12687 ALR Dm, DmelCG11579, CG11579, beta-catenin, ctnnb1, MGC79992, MGC132060, Cibeta-catenin, CTNNB1, MGC52601, LOC576711, Ctnnb1, MGC139922

Anwendungen

Applikationshinweise Western Blotting. Immunoprecipitation. Immunohistochemistry on Paraffin Sections: 1/250 for 10 min at RT. Staining offormalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10min followed by cooling at RT for 20 min. Positive Control: Breast carcinoma. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Konzentration 0.2 mg/ml
Reinigung Purified
Buffer 10mM PBS, pH 7.4 with BSA and Sodium Azide.
Lagerung Store the antibody undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.
Forschungsgebiet Signaltransduktion
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen

Alternativen zu Antigen "beta-Catenin (CTNNB1)", Typ "Antikörper" finden
Wirte Kaninchen (186), Maus (62)
Reaktivitäten Human (230), Maus (154), Ratte (Rattus) (138), Huhn (29), Hund (13), Rind (Kuh) (8), Schwein (6), Xenopus laevis (5), Hamster (2), Affe (1), Kaninchen (1), Schaf (1)
Applikationen Western Blot (WB) (219), Immunfluoreszenz (IF) (72), Immunpräzipitation (IP) (62), Enzyme Immunoassay (EIA) (52), Immunhistochemie (Paraffinschnitte) (IHC (p)) (49), Immunhistochemie (IHC) (40), ELISA (30), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (20), Durchflusszytometrie (FACS) (19), Dot Blot (Dot) (8), Immunzytochemie (ICC) (5), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Elektromobilitäts-Experimente (EMSA) (1), Immunoelectron Microscopy (IEM) (1)
Konjugate Biotin (5), Cy3 (2), FITC (2), HRP (2), Alexa Flour 488 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), Gold (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1), RBITC (1)
Epitope pSer33 (10), pSer37 (10), Ab-33 (5), Ab-37 (5), Ab-41/45 (5), pSer33/37 (5), pThr41/Ser45 (5), pThr41/pSer45 (5), C-Term (4), Ab-654 (3), pTyr654 (3), pTyr86 (3), exon 3 (2), pSer45 (2), Ab-489 (1), Core (1), dep27-37 (1), dep35-50 (1), pTyr489 (1)