RPS6KA3 Antikörper (C-Term)

Produktnummer ABIN372713

Produktdetails anti-RPS6KA3 Antikörper

Target: RPS6KA3 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Huhn

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RPS6KA3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody recognizes the ~90k RSK2 protein.

Kreuzreaktivität (Details): Species reactivity (expected):Bovine, Canine, Chicken, Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity Chromatography.

Immunogen: Peptide corresponding to amino acid residues from the C-terminal region of rat RSK2, conjugated to keyhole limpet hemocyanin (KLH).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot: 1/1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody undiluted (in aliquots) at-20 °C.

Details zu RPS6KA3

Target: RPS6KA3 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3))

Andere Bezeichnung: RPS6KA3 / RSK2 (RPS6KA3 Produkte)

Synonyme: HU-1 antikoerper, MAPKAPK1A antikoerper, RSK antikoerper, RSK1 antikoerper, CLS antikoerper, HU-3 antikoerper, ISPK-1 antikoerper, MAPKAPK1B antikoerper, MRX19 antikoerper, RSK2 antikoerper, S6K-alpha3 antikoerper, p90-RSK2 antikoerper, pp90RSK2 antikoerper, MPK-9 antikoerper, Rsk2 antikoerper, RGD1563860 antikoerper, id:ibd1103 antikoerper, rps6ka3 antikoerper, si:ch211-114c12.12 antikoerper, wu:fk86e02 antikoerper, zgc:56006 antikoerper, zgc:158386 antikoerper, ribosomal protein S6 kinase A1 antikoerper, ribosomal protein S6 kinase A3 antikoerper, ribosomal protein S6 kinase polypeptide 3 antikoerper, ribosomal protein S6 kinase a, polypeptide 3a antikoerper, ribosomal protein S6 kinase, polypeptide 3b antikoerper, RPS6KA1 antikoerper, RPS6KA3 antikoerper, Rps6ka3 antikoerper, rps6ka3a antikoerper, rps6ka3b antikoerper

Hintergrund: The p90 Ribosomal S6 kinases (RSK1-4) are downstream members of the extracellular signal-regulated kinase (ERK)/MAPK cascade. The loss of RSK2 activity in humans leads to Coffin-Lowry syndrome, which is characterized by mental retardation and growth deficits (Hanauer and Young, 2002). Recent work suggests that RSK2 exerts a tonic regulation on G-protein coupled signaling (Sheffler et al., 2006).Synonyms: ISPK-1, ISPK1, MAPKAPK-1b, MAPKAPK1, RSK-2, Ribosomal S6 kinase 2, Ribosomal protein S6 kinase alpha-3, S6K-alpha-3, p90RSK3

Gen-ID: 6197

NCBI Accession: NP_004577

UniProt: P51812

Pathways: MAPK Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades