TACI Antikörper (AA 116-132)

Produktnummer ABIN372462

Produktdetails anti-TACI Antikörper

Target: TACI (TNFRSF13B) (Tumor Necrosis Factor Receptor Superfamily, Member 13B (TNFRSF13B))

Bindungsspezifität: AA 116-132

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TACI Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody recognizes CD267/TACI.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse.
Species reactivity (tested):Human.

Aufreinigung: Protein G Chromatography.

Immunogen: Synthetic peptide corresponding to amino acids 116-132 of human TACI.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on Paraffin Sections: 5 μg/mL. Western blot: 5 μg/mL. Flow Cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.2 % Gelatin as stabilizer and 0.05 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu TACI

Target: TACI (TNFRSF13B) (Tumor Necrosis Factor Receptor Superfamily, Member 13B (TNFRSF13B))

Andere Bezeichnung: CD267 / TACI (TNFRSF13B Produkte)

Synonyme: CD267 antikoerper, CVID antikoerper, CVID2 antikoerper, RYZN antikoerper, TACI antikoerper, TNFRSF14B antikoerper, TNFRSF13B antikoerper, 1200009E08Rik antikoerper, Taci antikoerper, TNF receptor superfamily member 13B antikoerper, tumor necrosis factor receptor superfamily, member 13b antikoerper, TNFRSF13B antikoerper, Tnfrsf13b antikoerper

Hintergrund: Simultaneously four different laboratories identified a a new member of the tumor necrosis factor (TNF) family. This has been named as TALL-1, THANK (TNF homologue that activates apoptosis, nuclear factor-kappaB, and c-Jun NH2-terminal kinase, BAFF (for B cell activating factor belonging to the TNF family) and BlyS (B lymphocyte stimulator). Membrane-bound BAFF is processed and secreted through the action of a protease whose specificity matches that of the furin family of proprotein convertases. The receptor for BlyS/BAFF appears to be expressed predominantly on B cells and activated T cells. Recently two orphan receptors TACI and BCMA have been shown to be receptors for BlyS/BAFF. TACI is expressed on B cells and signals through CAML, activating the transcription factors NF-AT, NF-kB, and AP-1. TACI is a type III transmembrane protein, as defined by the lack of a cleaved signal sequence and its N-terminal extracellular exposure. The cDNA codes for 293 amino acids with predicted molecular weight of approximately 32 kDa.Synonyms: TNFRSF13B, Transmembrane activator and CAML interactor, Tumor necrosis factor receptor superfamily member 13B

Gen-ID: 23495

NCBI Accession: NP_036584

UniProt: O14836