ZMYM2 Antikörper (AA 1250-1300)

Produktnummer ABIN372247

Produktdetails anti-ZMYM2 Antikörper

Target: ZMYM2 (Zinc Finger, MYM-Type 2 (ZMYM2))

Bindungsspezifität: AA 1250-1300

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Huhn, Affe, Orang-Utan

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZMYM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody recognizes Zinc Finger Protein 198 (ZNF198) (ZMYM2).

Kreuzreaktivität (Details): Species reactivity (expected):Bovine, Chicken, Dog, Monkey, Mouse, Orangutan and RatSpecies reactivity (tested):Human.

Aufreinigung: Immunoaffinity Chromatography.

Immunogen: Synthetic peptide corresponding to the amino acids 1250-1300 of human Zinc finger protein 198.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on Paraffin Sections: 10 μg/mL. Western Blot: 0.1-1.0 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % Sodium Azide as preservative and 0.2 % Gelatin as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu ZMYM2

Target: ZMYM2 (Zinc Finger, MYM-Type 2 (ZMYM2))

Andere Bezeichnung: ZMYM2 (ZMYM2 Produkte)

Synonyme: ZMYM2 antikoerper, ZNF198 antikoerper, fc07a10 antikoerper, wu:fc07a10 antikoerper, si:dkey-51d17.6 antikoerper, fim antikoerper, mym antikoerper, ramp antikoerper, scll antikoerper, zfp198 antikoerper, znf198 antikoerper, MGC83724 antikoerper, FIM antikoerper, MYM antikoerper, RAMP antikoerper, SCLL antikoerper, 5830413P05Rik antikoerper, Zfp198 antikoerper, Znf198 antikoerper, zinc finger MYM-type containing 2 antikoerper, zinc finger, MYM-type 2 antikoerper, zinc finger MYM-type containing 2 L homeolog antikoerper, ZMYM2 antikoerper, zmym2 antikoerper, zmym2.L antikoerper, Zmym2 antikoerper

Hintergrund: Zfp198 (zinc finger protein 198, also known as ZNF198 or Zinc finger MYM-type protein 2) is a transcription factor that contains 9 MYM-type zinc fingers. Zfp198 interacts with, and is modified by, SUMO1 and colocalises with PML to nuclear bodies. Zfp198 has also been shown to stabilise the LSD1-CoREST-HDAC1 complex on chromatin through its MYM-type zinc fingers. A chromosomal translocation resulting in a Zfp198-FGFR1 fusion is associated with stem cell leukemia lymphoma syndrome (SCLL). SCLL usually presents as a lymphoblastic lymphoma in association with a myeloproliferative disorder.Synonyms: FIM, Fused in myeloproliferative disorders protein, RAMP, Rearranged in atypical myeloproliferative disorder protein, ZNF198, Zinc finger MYM-type protein 2, Zinc finger protein 198

Gen-ID: 7750

NCBI Accession: NP_001177893

UniProt: Q9UBW7