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FADD Antikörper (Sepharose)

FADD Reaktivität: Human WB, IP, EIA Wirt: Maus Monoclonal 1A11 Sepharose
Produktnummer ABIN371639
  • Target Alle FADD Antikörper anzeigen
    FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
    Reaktivität
    • 90
    • 61
    • 19
    • 18
    • 15
    Human
    Wirt
    • 98
    • 20
    Maus
    Klonalität
    • 94
    • 24
    Monoklonal
    Konjugat
    • 71
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FADD Antikörper ist konjugiert mit Sepharose
    Applikation
    • 92
    • 51
    • 33
    • 15
    • 15
    • 15
    • 14
    • 11
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody is specific for FADD.
    Produktmerkmale
    Synonyms: FAS-associated death domain protein, MORT1, GIG3, FAS-associating deathdomain-containing protein, Mediator of receptor induced toxicity, Growth-inhibiting gene 3protein
    Klon
    1A11
    Isotyp
    IgG1
    Top Product
    Discover our top product FADD Primärantikörper
  • Applikationshinweise
    ELISA. Immunoprecipitation. Western Blot.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    2 mLof 100 mM Borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Store protected from light. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    Haltbarkeit
    12 months
  • Target
    FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
    Andere Bezeichnung
    FADD (FADD Produkte)
    Synonyme
    MORT1 antikoerper, Mort1/FADD antikoerper, Mort1 antikoerper, TNFRSF6 antikoerper, adaptor antikoerper, fadd antikoerper, mort1 antikoerper, xfadd antikoerper, Fas associated via death domain antikoerper, Fas (TNFRSF6)-associated via death domain antikoerper, Fas associated via death domain S homeolog antikoerper, Fas (tnfrsf6)-associated via death domain antikoerper, FADD antikoerper, Fadd antikoerper, fadd.S antikoerper, fadd antikoerper
    Hintergrund
    Fas-associated death domain (FADD, also known as MORT1) is an important apoptosis adapter molecule involved in the Fas-mediated cell death pathway. FADD associates with the intracellular domain of FAS (CD95/APO-1) through their respective C-terminal death domains (DD). The N-terminal region of FADD contains a death effectors domain (DED) which recruits and binds cytosolic proteins such as FLICE/caspase-8. The subsequent activation of FLICE by proteolytic cleavage leads to the activation of the caspase-mediated (ICE-related proteases) apoptotic cascade. Overexpression of FADD induces apoptosis which is inhibited by CrmA, a specific inhibitor of the interleukin-1a-converting enzyme. FADD has also been shown under certain circumstances to promote cell survival and proliferation. (Ref.1-6)Synonyms: FAS-associated death domain protein, FAS-associating death domain-containing protein, GIG3, Growth-inhibiting gene 3 protein, MORT1, Mediator of receptor induced toxicity
    Gen-ID
    8772
    UniProt
    Q13158
    Pathways
    Apoptose, TLR Signalweg, Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades
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