MHC, Class I Antikörper

Produktnummer ABIN371396

Der Maus Monoklonal anti-MHC, Class I Antikörper wird verwendet zum Nachweis von MHC, Class I in Proben von Huhn und Pute. Er wurde validiert für FACS, WB, IP und IHC (fro).

Kurzübersicht für MHC, Class I Antikörper (ABIN371396)

Target: MHC, Class I

Reaktivität: Huhn, Pute

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MHC, Class I Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: F21-2

Produktdetails anti-MHC, Class I Antikörper

Produktmerkmale: Synonyms: MHC class I-alpha, Major Histocompatibility Complex Class I

Aufreinigung: Purified

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow Cytometry. (Ref.1-4)Immunoprecipitation. (Ref.1-3)Immunohistochemistry on Frozen Sections. Western Blot. Immunoaffinity Chromatography.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu MHC, Class I

Target: MHC, Class I

Andere Bezeichnung: MHC Class I

Hintergrund: MHC Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. MHC class I antigens are heterodimers consisting of one alpha chain (44 kDa) with beta 2 microglobulin (11.5 kDa). The antigen is expressed by all somatic cells at varying levels. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. (Ref.1-3)Fibroblasts or neurons however only show a low level of antigen.Synonyms: HLA Class 1, MHC Class 1, Major Histocompatibility complex class I