Flow Cytometry: < / 3 μg/10^6 cells. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
0.5 mg/mL
Buffer
PBS containing 0.09 % Sodium Azide as preservative.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Haltbarkeit
12 months
Target
TNFRSF8
(Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8))
CD30 antikoerper, D1S166E antikoerper, Ki-1 antikoerper, Cd30 antikoerper, Ki antikoerper, TNFRSF8 antikoerper, TNF receptor superfamily member 8 antikoerper, tumor necrosis factor receptor superfamily, member 8 antikoerper, TNFRSF8 antikoerper, Tnfrsf8 antikoerper
Hintergrund
CD30 is a type I transmembrane protein and a member of the tumor necrosis factor receptor superfamily of proteins. (Ref.1,2) Murine CD30 is expressed predominantly in the thymus, and it is inducible in mouse splenocytes stimulated with pokeweed mitogen or concanavalin A. (Ref.1) In anti-CD3e-activated spleen cells, CD30 is expressed primarily on the surface of CD8+ T cells with peak expression on days 4 and 5. Stimulation of CD30+ CTL lines with plate-bound anti-CD30 directly signals IL-5 but not IFN-gamma production. (Ref.1) While these studies demonstrate that CD30 directs cytokine secretion and suggest that CD30 may play a pivotal role in the pattern of cytokine production by T cells, the precise roles of CD30 and its ligand (CD153) in T-cell development have not been clearly defined.Synonyms: CD30L receptor, D1S166E, KI-1 antigen, Lymphocyte activation antigen CD30, TNFRSF8, Tumor necrosis factor receptor superfamily member 8