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NFKB1 Antikörper (AA 925-929)

NFKB1 Reaktivität: Human, Maus, Ratte WB, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN363027
  • Target Alle NFKB1 Antikörper anzeigen
    NFKB1 (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1))
    Bindungsspezifität
    • 35
    • 29
    • 28
    • 28
    • 16
    • 16
    • 16
    • 16
    • 15
    • 13
    • 7
    • 7
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 925-929
    Reaktivität
    • 322
    • 177
    • 154
    • 11
    • 8
    • 7
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 319
    • 21
    • 1
    • 1
    Kaninchen
    Klonalität
    • 314
    • 28
    Polyklonal
    Konjugat
    • 142
    • 21
    • 16
    • 16
    • 16
    • 16
    • 16
    • 16
    • 15
    • 12
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 2
    Dieser NFKB1 Antikörper ist unkonjugiert
    Applikation
    • 181
    • 118
    • 118
    • 105
    • 103
    • 68
    • 62
    • 36
    • 28
    • 14
    • 12
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Spezifität
    The antibody detects endogenous level of total NFkB-p105 protein.
    Aufreinigung
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.
    Immunogen
    Peptide sequence around AA 925-929 (C-D-S-G-V ) derived from Human NFkB-p105. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
    Isotyp
    IgG
    Top Product
    Discover our top product NFKB1 Primärantikörper
  • Applikationshinweise
    Western blotting: 1:500-1:1000
    Immunofluorescence: 1:100-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Target
    NFKB1 (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1))
    Andere Bezeichnung
    NFkappaB-p105/p50 (NFKB1 Produkte)
    Synonyme
    GKLP antikoerper, NKTL antikoerper, NTKL antikoerper, P105 antikoerper, TAPK antikoerper, TEIF antikoerper, TRAP antikoerper, EBP-1 antikoerper, KBF1 antikoerper, NF-kB1 antikoerper, NF-kappa-B antikoerper, NF-kappaB antikoerper, NFKB-p105 antikoerper, NFKB-p50 antikoerper, NFkappaB antikoerper, p105 antikoerper, p50 antikoerper, NF-kB antikoerper, NF-KB1 antikoerper, ebp-1 antikoerper, kbf1 antikoerper, nf-kappa-b antikoerper, nf-kappaB antikoerper, nfkb-p105 antikoerper, nfkb-p50 antikoerper, NF-kappaB1 antikoerper, p50/p105 antikoerper, BICDR-1 antikoerper, bicdr1 antikoerper, ccdc64 antikoerper, SCY1 like pseudokinase 1 antikoerper, nuclear factor kappa B subunit 1 antikoerper, nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 L homeolog antikoerper, nuclear factor NF-kappa-B p105 subunit antikoerper, nucleoporin 107 antikoerper, nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 antikoerper, nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 antikoerper, SCYL1 antikoerper, NFKB1 antikoerper, Nfkb1 antikoerper, nfkb1.L antikoerper, CpipJ_CPIJ012236 antikoerper, Nup107 antikoerper, nfkb1 antikoerper
    Hintergrund
    NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively.
    Molekulargewicht
    120 kDa
    NCBI Accession
    NP_001158
    UniProt
    P19838
    Pathways
    p53 Signalweg, NF-kappaB Signalweg, RTK Signalweg, T-Zell Rezeptor Signalweg, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Toll-Like Receptors Cascades, BCR Signaling, S100 Proteine
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