PRKAA1/PRKAA2 Antikörper (AA 170-174, AA 172-176)
Kurzübersicht für PRKAA1/PRKAA2 Antikörper (AA 170-174, AA 172-176) (ABIN362825)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 170-174, AA 172-176
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Spezifität
- The antibody detects endogenous level of total AMPKa1/AMPKa2 protein.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.
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Immunogen
- Peptide sequence around AA 172-176, 170-174 (L-R-T-S-C) derived from Human AMPKa1, AMPKa2. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
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Isotyp
- IgG
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anti-AMPK1/AMPK2 (pThr172), (pThr183) antibody
Reaktivität: Human, Maus, Ratte, Affe WB, IF, ELISA, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-AMPK1/AMPK2 (pThr172), (pThr183) antibodyReaktivität: Human, Maus, Ratte, Schwein, Schaf WB, ELISA, IF (cc), IHC (p), FACS, IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-AMPK1/AMPK2 (AA 14-47), (N-Term) antibodyReaktivität: Maus WB Wirt: Kaninchen Polyclonal RB43852 unconjugated
anti-AMPK1/AMPK2 (Ser1071) antibodyReaktivität: Human, Maus, Ratte, Affe WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-AMPK1/AMPK2 (pThr172), (pThr183) antibody (Cy7)Reaktivität: Human, Maus, Ratte, Schwein, Schaf WB, IF (cc), FACS, IF (p) Wirt: Kaninchen Polyclonal Cy7
anti-AMPK1/AMPK2 (Catalytic Domain), (N-Term) antibodyReaktivität: Human, Maus, Ratte, Drosophila melanogaster, Vertebrate WB, IF, ELISA, IHC (fro), IP Wirt: Maus Monoclonal 84-1 unconjugated
anti-AMPK1/AMPK2 (pThr172), (pThr183) antibodyReaktivität: Human, Maus, Ratte, Schwein, Affe, Penaeus japonicus WB, IHC, IF, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-AMPK1/AMPK2 (Center) antibodyReaktivität: Human, Maus, Ratte, Schwein, Huhn WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-AMPK1/AMPK2 (pThr172), (pThr183) antibodyReaktivität: Human, Maus, Ratte, Schwein, Huhn WB, IHC Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
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Western blotting: 1:500-1:1000
Immunohistochemistry: 1:50-1:100
Immunofluorescence: 1:100-1:200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- PRKAA1/PRKAA2 (AMPK1/AMPK2)
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Andere Bezeichnung
- AMPKalpha1/AMPKalpha2
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Hintergrund
- Responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. Appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. This is a catalytic subunit.
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Molekulargewicht
- 63 kDa
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NCBI Accession
- NP_006243, NP_006242
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UniProt
- Q13131
Target
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