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ZAP70 Antikörper (AA 491-495)

ZAP70 Reaktivität: Human, Maus, Ratte IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN362798
  • Target Alle ZAP70 Antikörper anzeigen
    ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))
    Bindungsspezifität
    • 41
    • 40
    • 26
    • 20
    • 20
    • 16
    • 14
    • 10
    • 10
    • 9
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 6
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 491-495
    Reaktivität
    • 296
    • 128
    • 48
    • 8
    • 7
    • 7
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    Human, Maus, Ratte
    Wirt
    • 219
    • 73
    • 2
    • 2
    • 1
    Kaninchen
    Klonalität
    • 197
    • 99
    Polyklonal
    Konjugat
    • 146
    • 18
    • 16
    • 16
    • 12
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ZAP70 Antikörper ist unkonjugiert
    Applikation
    • 202
    • 131
    • 102
    • 69
    • 53
    • 53
    • 49
    • 27
    • 27
    • 22
    • 14
    • 12
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC)
    Spezifität
    The antibody detects endogenous level of total Zap-70 protein.
    Aufreinigung
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    Immunogen
    Peptide sequence around AA 491-495 (S-Y-Y-T-A) derived from Human ZAP70. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
    Isotyp
    IgG
    Top Product
    Discover our top product ZAP70 Primärantikörper
  • Applikationshinweise
    Western blotting: 1:500-1:1000
    Immunohistochemistry: 1:50-1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Target
    ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))
    Andere Bezeichnung
    Zap-70 (ZAP70 Produkte)
    Synonyme
    SRK antikoerper, STCD antikoerper, STD antikoerper, TZK antikoerper, ZAP-70 antikoerper, 70kDa antikoerper, AI327364 antikoerper, Srk antikoerper, mrtle antikoerper, mur antikoerper, zap70 antikoerper, MGC80670 antikoerper, MGC88962 antikoerper, ZAP70 antikoerper, zgc:110383 antikoerper, zeta chain of T-cell receptor associated protein kinase 70 antikoerper, putative tyrosine-protein kinase zap-70 antikoerper, zeta-chain (TCR) associated protein kinase antikoerper, zeta chain of T cell receptor associated protein kinase 70 antikoerper, zeta-chain (TCR) associated protein kinase 70kDa antikoerper, zeta chain of T cell receptor associated protein kinase 70kDa L homeolog antikoerper, zeta chain of T cell receptor associated protein kinase 70kDa antikoerper, tyrosine-protein kinase ZAP-70 antikoerper, ZAP70 antikoerper, Smp_149470 antikoerper, Zap70 antikoerper, zap70.L antikoerper, zap70 antikoerper, LOC707555 antikoerper, LOC100342021 antikoerper, LOC100390922 antikoerper, LOC100542877 antikoerper
    Hintergrund
    ZAP70 is a 70-kD tyrosine phosphoprotein that associates with the zeta chain and undergoes tyrosine phosphorylation following TCR stimulation. The ZAP70 gene is expressed in T- and natural KILLER cells. Protein-Tyrosine Kinases (PTKs) play an integral role in T-cell activation. Stimulation of the T-cell antigen receptor results in tyrosine phosphorylation of a number of cellular substrates. One of these is the TCR-zeta chain, which can mediate the transduction of extracellular stimuli into cellular effector functions
    Molekulargewicht
    70 kDa
    UniProt
    P43403
    Pathways
    T-Zell Rezeptor Signalweg, Ubiquitin Proteasome Pathway
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