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PAK1 Antikörper (AA 210-214)

PAK1 Reaktivität: Human, Ratte, Maus WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN362773
  • Target Alle PAK1 Antikörper anzeigen
    PAK1 (P21-Activated Kinase 1 (PAK1))
    Bindungsspezifität
    • 34
    • 17
    • 15
    • 13
    • 10
    • 10
    • 9
    • 9
    • 8
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 210-214
    Reaktivität
    • 173
    • 94
    • 82
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Human, Ratte, Maus
    Wirt
    • 166
    • 4
    • 1
    • 1
    Kaninchen
    Klonalität
    • 160
    • 13
    Polyklonal
    Konjugat
    • 90
    • 10
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    Dieser PAK1 Antikörper ist unkonjugiert
    Applikation
    • 116
    • 66
    • 44
    • 39
    • 39
    • 34
    • 31
    • 14
    • 11
    • 10
    • 10
    • 6
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Spezifität
    The antibody detects endogenous level of total PAK1protein.
    Aufreinigung
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.
    Immunogen
    Peptide sequence around AA 210-214 (P-V-T-P-T) derived from Human PAK1. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
    Isotyp
    IgG
    Top Product
    Discover our top product PAK1 Primärantikörper
  • Applikationshinweise
    Western blotting: 1:500-1:1000
    Immunohistochemistry: 1:50-1:100
    Immunofluorescence: 1:100-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Wang, Ma, Xu, Wang, Zhu, An, An, Wu, Tian: "Phosphorylation of histone H3 on Ser10 by auto-phosphorylated PAK1 is not essential for chromatin condensation and meiotic progression in porcine oocytes." in: Journal of animal science and biotechnology, Vol. 4, Issue 1, pp. 13, (2013) (PubMed).

  • Target
    PAK1 (P21-Activated Kinase 1 (PAK1))
    Andere Bezeichnung
    PAK1 (PAK1 Produkte)
    Synonyme
    X-PAK1 antikoerper, XPak1 antikoerper, pak antikoerper, pak-1 antikoerper, pakalpha antikoerper, PAKalpha antikoerper, AW045634 antikoerper, PAK-1 antikoerper, Paka antikoerper, p21 protein (Cdc42/Rac)-activated kinase 1 S homeolog antikoerper, p21 (RAC1) activated kinase 1 antikoerper, p21 protein (Cdc42/Rac)-activated kinase 1 antikoerper, Serine/threonine-protein kinase pak-1 antikoerper, pak1.S antikoerper, PAK1 antikoerper, Pak1 antikoerper, pak-1 antikoerper
    Hintergrund
    The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB. Activity is inhibited in cells undergoing apoptosis, potentially due to binding of CDC2L1 and CDC2L2.
    Molekulargewicht
    68 kDa
    NCBI Accession
    NP_001122
    UniProt
    Q13153
    Pathways
    MAPK Signalweg, RTK Signalweg, T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Embryonic Body Morphogenesis
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