HDAC4 Antikörper (AA 630-634)

Produktnummer ABIN362743

Produktdetails anti-HDAC4 Antikörper

Target: HDAC4 (Histone Deacetylase 4 (HDAC4))

Bindungsspezifität: AA 630-634

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HDAC4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Spezifität: The antibody detects endogenous level of total HDAC4 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.

Immunogen: Peptide sequence around AA 630-634 (A-Q-S-S-P) derived from Human HDAC4. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blotting: 1:500-1:1000
Immunofluorescence: 1:100-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu HDAC4

Target: HDAC4 (Histone Deacetylase 4 (HDAC4))

Andere Bezeichnung: HDAC4 (HDAC4 Produkte)

Synonyme: CG1770 antikoerper, DHDAC4 antikoerper, Dmel\\CG1770 antikoerper, GC1770 antikoerper, HDAC antikoerper, HDAC4a antikoerper, dHDAC4 antikoerper, dmHDA405 antikoerper, hdac4 antikoerper, dana_GLEANR_19966 antikoerper, DanaGF18710 antikoerper, GF18710 antikoerper, HDAC4 antikoerper, AHO3 antikoerper, BDMR antikoerper, HA6116 antikoerper, HD4 antikoerper, HDAC-4 antikoerper, HDAC-A antikoerper, HDACA antikoerper, 4932408F19Rik antikoerper, AI047285 antikoerper, wu:fa96d08 antikoerper, wu:fc56f08 antikoerper, zgc:152701 antikoerper, histone deacetylase 4 antikoerper, hypothetical protein antikoerper, Histone deacetylase 4 antikoerper, GF18710 gene product from transcript GF18710-RC antikoerper, PTRG_03699 antikoerper, PGTG_15512 antikoerper, HDAC4 antikoerper, Dana\GF18710 antikoerper, Hdac4 antikoerper, hdac4 antikoerper

Hintergrund: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.

Molekulargewicht: 140 kDa

NCBI Accession: NP_006028

UniProt: P56524

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process