Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 3 (HCN3) Antikörper

Antigen: Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 3 (HCN3)

Synonyme: CNG3, ACHM2, CCNC1, CCNCa, CNCG3, CCNCalpha, Hac3, Hcn4, Bcng4, BCNG-4, KIAA1535, MGC131493, CNGA3, HCN3

Klonalität: Monoklonal (S141-28)

Wirt: Maus

Reaktivität: Human, Maus, Ratte (Rattus)

Applikation: Western Blot (WB), Immunzytochemie (ICC), Immunhistochemie (IHC)

Produktnummer: ABIN361765

Produktbeschreibung

Produktmerkmale: Detects ~90kDa. No cross-reactivity against other HCNs

Weitere Bezeichnung: HCN3

Gen-ID: 15168

Swiss-Prot: O88705

Immunogen: Fusion protein amino acids 660-779 (C terminus) of mouse HCN3, accession number O88705

Format: Liquid

Isotyp: IgG1  (Passende Sekundärantikörper)

Klon: S141-28

Beschreibung: Hyperpolarization-activated cation channels of the HCN gene family contribute to spontaneous rhythmic activity in both the heart and brain.
Synonyms: KIAA1535, potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3

Spezifität: ~90kDa. No cross reactivity against other HCNs. Species cross-reactivity: Mouse, Rat.

Sensitivität: 1 µg/mL of SMC-306 was sufficient for detection of HCN3 in 10µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Anwendungen

Applikationshinweise: 1-10ug/mL (WB), 0.1-1.0ug/mL (Perox) (IHC/ICC), 1.0-10ug/mL (IF)

Konzentration: 1 mg/mL

Reinigung: Protein G Purified

Buffer: PBS pH7.4, 50% glycerol

Lagerung: -20 °C

Storage Shipping Temp Max: Blue Ice or 4 °C

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

HCN3 (S141-28), Human hippocampus

Publikationen

Publikationen: Zong, Eckert, Yuan et al.: "A novel mechanism of modulation of hyperpolarization-activated cyclic nucleotide-gated channels by Src kinase." in: The Journal of biological chemistry, Vol. 280, Issue 40, pp. 34224-32, 2005 (PubMed).