»
Antikörper
»
anti-BCL2 Binding Component 3 (BBC3) Antikörper
BCL2 Binding Component 3 (BBC3) Antikörper
| Antigen |
|
| Synonyme |
JFY1, PUMA, PUMA/JFY1, BBC3 |
| Klonalität |
Polyklonal |
|
Wirt
|
|
|
Reaktivität
|
|
|
Applikation
|
Western Blot (WB) (46), Immunfluoreszenz (IF) (6), Enzyme Immunoassay (EIA) (5), Immunhistochemie (Paraffinschnitte) (IHC (p)) (4), ELISA (3), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (3), Immunpräzipitation (IP) (3), Durchflusszytometrie (FACS) (2), Immunzytochemie (ICC) (2), Immunhistochemie (IHC) (2), Dot Blot (Dot) (1)
|
| Produktnummer |
ABIN361754 |
| Menge |
100ug (1.0mg/mL) (Varianten) |
| Preis |
278,02 € Zzgl. Versandkosten €20,00 und MWSt
|
| Lieferung nach |
|
| Verfügbarkeit |
Lieferung in 5 bis 7 Werktagen |
, in K562 human cell lysate.jpg)
|
Weitere Bezeichnung
|
Puma
|
|
Immunogen
|
N-terminal amino acids of human PUMA
|
|
Format
|
Affinity-purified
|
|
Beschreibung
|
Apoptosis is related to many diseases and development. The p53 tumor-suppressor protein induces apoptosis through transcriptional activation of several genes. A novel p53 inducible pro-apoptotic gene was identified recently and designated PUMA (for p53 up-regulated modulator of apoptosis) and bbc3 (for Bcl-2 binding component 3) in human and mouse (1-3). PUMA/bbc3 is one of the pro-apoptotic Bcl-2 family members including Bax and Noxa, which are also transcriptional targets of p53. The PUMA gene encodes two BH3 domain-containing proteins termed PUMA-a and PUMA-
|
|
Spezifität
|
Detects a 23 kDa protein corresponding to the molecular mass of PUMA on SDS PAGE immunoblots. Species cross-reactivity: Human.
|
|
Applikationshinweise
|
Suggested dilution 1: 500 for Western blots, 1:100 for ICC.
|
|
Konzentration
|
1.0mg/mL
|
|
Buffer
|
Affinity purified in PBS with 0.02% Sodium Azide
|
|
Lagerung
|
-20°C, 1 year+, shipped on cold packs or ambient
|
|
Forschungsgebiet
|
Apoptose/Nekrose
|
|
Beschränkungen
|
Nur für Forschungszwecke einsetzbar
|
Alternativen zu Antigen "BCL2 Binding Component 3 (BBC3)", Typ "Antikörper" finden
|
Wirte
|
Kaninchen (42), Maus (5), Ziege (1)
|
|
Reaktivitäten
|
Human (44), Maus (19), Ratte (Rattus) (3), Rind (Kuh) (1)
|
|
Applikationen
|
Western Blot (WB) (46), Immunfluoreszenz (IF) (6), Enzyme Immunoassay (EIA) (5), Immunhistochemie (Paraffinschnitte) (IHC (p)) (4), ELISA (3), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (3), Immunpräzipitation (IP) (3), Durchflusszytometrie (FACS) (2), Immunzytochemie (ICC) (2), Immunhistochemie (IHC) (2), Dot Blot (Dot) (1)
|
|
Konjugate
|
Biotin (1), HRP (1)
|
|
Epitope
|
Alpha isoform (3), BH3 Domain (1)
|
Alternativen , in K562 human cell lysate.jpg)
