DnaJ (Hsp40) Homolog, Subfamily B, Member 1 (DNAJB1) Antikörper

Antigen: DnaJ (Hsp40) Homolog, Subfamily B, Member 1 (DNAJB1)

Synonyme: DNAJ1, DROJ1, DnaJ1 64EF, EU3500, HSP40, HSP40/HDJ1, Hsp-40, anon-WO0140519.166, anon-WO0172774.135, dHDJ1, dHDJ1/HSP40, dhdj-1, DmelCG10578, CG10578, psiHSP40, hdj1, sis1, hsp40, hspf1, dnajb4, MGC89364, Hsp40, DnaJ-5, MAS5, dnaJ

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Western Blot (WB), Immunpräzipitation (IP)

Produktnummer: ABIN361670

Produktbeschreibung

Produktmerkmale: Detects an ~40kDa protein corresponding to the molecular mass of Hsp40 on SDS PAGE immunoblots. Also detects recombinant Hsp40.

Weitere Bezeichnung: Hsp40

Gen-ID: NP_006136.1, 3337

Immunogen: Recombinant purified human hsp40

Format: Liquid

Beschreibung: DnaJ/Hsp40 proteins have been preserved throughout evolution and are important for protein translation, folding, unfolding, translocation, and degradation, primarily by stimulating the ATPase activity of chaperone proteins, Hsp70s. Because the ATP hydrolysis is essential for the activity of Hsp70s, DnaJ/Hsp40 proteins actually determine the activity of Hsp70s by stabilizing their interaction with substrate proteins. DnaJ/Hsp40 proteins all contain the J domain through which they bind to Hsp70s. Hsp40, also known as HDJ1 (6), is a basic mammalian 40kDa heat shock protein which is not only homologous to the bacterial heat shock protein (DnaJ), but also yeast DnaJ-related proteins such as SCJ1, Sec63/Npl1, YDJ1 and SIS1 (2-5). Hsp 40 is inducible by stress including heat after which is moves from the cytoplasm to the nucleus and nucleoli, an intracellular pattern similar to Hsc70/Hsp70, the mammalian homologues of the bacterial heat shock protein, DnaK (2).
Synonyms: DnaJ (Hsp40) homolog subfamily B member 1, DNAJ1, DNAJB1, HDJ1, HSPF1

Spezifität: Detects a 40kDa protein corresponding to the molecular mass of hsp40 on SDS PAGE immunoblots, also detects recombinant hsp40. Species cross-reactivity: Human (1), Mouse, Rat, and African green Monkey.

Synonyme: DNAJ1, DROJ1, DnaJ1 64EF, EU3500, HSP40, HSP40/HDJ1, Hsp-40, anon-WO0140519.166, anon-WO0172774.135, dHDJ1, dHDJ1/HSP40, dhdj-1, DmelCG10578, CG10578, psiHSP40, hdj1, sis1, hsp40, hspf1, dnajb4, MGC89364, Hsp40, DnaJ-5, MAS5, dnaJ

Anwendungen

Applikationshinweise: 1: 1500-2,000 working dilution for Western Blot analysis

Reinigung: Antiserum

Lagerung: -20 °C

Storage Shipping Temp Max: Blue Ice or 4 °C

Forschungsgebiet: Hitzeschockproteine

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Hsp40, heat shocked Hela