ATPase, Ca++ Transporting, Type 2C, Member 1 (ATP2C1) Antikörper

Antigen: ATPase, Ca++ Transporting, Type 2C, Member 1 (ATP2C1)

Synonyme: HHD, BCPM, PMR1, SPCA1, hSPCA1, ATP2C1A, KIAA1347, MGC93231, SPCA, pmr1, AW061228, MGC58010, 1700121J11Rik, D930003G21Rik, ATP2C1, DKFZp469K1214

Klonalität: Polyklonal

Wirt: Maus

Reaktivität: Human

Applikation: Western Blot (WB), Immunfluoreszenz (IF)

Produktnummer: ABIN361612

Produktbeschreibung

Weitere Bezeichnung: ATP2C1

Gen-ID: 27032

Immunogen: Recombinant protein of full length Human ATP2C1

Format: Affinity-purified

Beschreibung: Function: This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of the calcium Subcellular location: Golgi apparatus membrane, Multi-pass membrane protein Tissue specificity: Found in most tissues except colon, thymus, spleen and leukocytes. Most abundant in keratinocytes and kidney Sequence similarities: Belongs to the cation transport ATPase (P-type) family.

Anwendungen

Applikationshinweise: WB: 1ug/ml. IF: 10ug/ml

Konzentration: 0.5 mg/ml

Reinigung: Protein A purified

Buffer: PBS, pH 7.2

Lagerung: Store below -20 degrees Celsius

Forschungsgebiet: Enzyme

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

ATP2C1 transfected 293T cell lysate

HeLa cell 0 0

Publikationen

Publikationen: Hu, Bonifas, Beech et al.: "Mutations in ATP2C1, encoding a calcium pump, cause Hailey-Hailey disease." in: Nature genetics, Vol. 24, Issue 1, pp. 61-5, 2000 (PubMed).

Sudbrak, Brown, Dobson-Stone et al.: "Hailey-Hailey disease is caused by mutations in ATP2C1 encoding a novel Ca(2+) pump." in: Human molecular genetics, Vol. 9, Issue 7, pp. 1131-40, 2000 (PubMed).

Fairclough, Dode, Vanoevelen et al.: "Effect of Hailey-Hailey Disease mutations on the function of a new variant of human secretory pathway Ca2+/Mn2+-ATPase (hSPCA1)." in: The Journal of biological chemistry, Vol. 278, Issue 27, pp. 24721-30, 2003 (PubMed).