G Protein-Coupled Receptor 77 (GPR77) Antikörper

Antigen: G Protein-Coupled Receptor 77 (GPR77)

Synonyme: C5L2, E030029A11Rik, Gpr77, GPR77, GPF77

Klonalität: Polyklonal

Wirt: Maus

Reaktivität: Human

Applikation: Western Blot (WB), Durchflusszytometrie (FACS)

Produktnummer: ABIN361605

Produktbeschreibung

Weitere Bezeichnung: GPR77

Gen-ID: 27202

Immunogen: Recombinant protein of full length Human GPR77

Format: Affinity-purified

Beschreibung: Function: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a, C4a and C3a and their desarginated derivatives.Couples weakly to Gi-mediated signaling pathways Subcellular location: Cell membrane, Multi-pass membrane protein Tissue specificity: Frontal cortex, hippocampus, hypothalamus, pons and liver Sequence similarities: Belongs to the G-protein coupled receptor 1 family.

Anwendungen

Applikationshinweise: WB: 1ug/ml. FACS: 1ug/ml

Konzentration: 0.5 mg/ml

Reinigung: Protein A purified

Buffer: PBS, pH 7.2

Lagerung: Store below -20 degrees Celsius

Forschungsgebiet: Signaltransduktion

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

GPR77 transfected 293T cell lysate. Negative control Transfectant

GPR77 expressing 293 cells 0 0

Publikationen

Publikationen: Lee, George, Cheng et al.: "Identification of four novel human G protein-coupled receptors expressed in the brain." in: Brain research. Molecular brain research, Vol. 86, Issue 1-2, pp. 13-22, 2001 (PubMed).

Cain, Monk: "The orphan receptor C5L2 has high affinity binding sites for complement fragments C5a and C5a des-Arg(74)." in: The Journal of biological chemistry, Vol. 277, Issue 9, pp. 7165-9, 2002 (PubMed).

Gerhard, Wagner, Feingold et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004 (PubMed).