Growth Factor Receptor-Bound Protein 7 (GRB7) Antikörper

Antigen: Growth Factor Receptor-Bound Protein 7 (GRB7)

Synonyme: KIAA4028, MGC78181, mKIAA4028, MGC93307, GRB7, MGC138032

Klonalität: Polyklonal

Wirt: Maus

Reaktivität: Human

Applikation: Western Blot (WB), Durchflusszytometrie (FACS)

Produktnummer: ABIN361568

Produktbeschreibung

Weitere Bezeichnung: GRB7

Gen-ID: 2886

Immunogen: Recombinant protein of full length Human GRB7

Format: Affinity-purified

Beschreibung: Function: Interacts with the cytoplasmic domain of the epidermal growth factor receptor which is then inhibited. The interaction is mediatedby the SH2 domain. Also binds to ERBB2 Sequence similarities: Belongs to the GRB7/10/14 family. Contains 1 PH domain. Contains 1 Ras-associating domain. Contains 1 SH2domain.

Anwendungen

Applikationshinweise: WB: 1ug/ml. FACS: 1ug/ml

Konzentration: 0.26 mg/ml

Reinigung: Protein A purified

Buffer: PBS, pH 7.2

Lagerung: Store below -20 degrees Celsius

Forschungsgebiet: Signaltransduktion

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

human stomach tissue lysate GRB7 transfected 293T cell lysate

human stomach tissue lysate GRB7 transfected 293T cell lysate

GRB7 expressing 293 cells. Negative control Transfectant

Publikationen

Publikationen: Tanaka, Mori, Akiyoshi et al.: "Coexpression of Grb7 with epidermal growth factor receptor or Her2/erbB2 in human advanced esophageal carcinoma." in: Cancer research, Vol. 57, Issue 1, pp. 28-31, 1997 (PubMed).

Kishi, Sasaki, Akiyama et al.: "Molecular cloning of human GRB-7 co-amplified with CAB1 and c-ERBB-2 in primary gastric cancer." in: Biochemical and biophysical research communications, Vol. 232, Issue 1, pp. 5-9, 1997 (PubMed).

Tanaka, Mori, Akiyoshi et al.: "A novel variant of human Grb7 is associated with invasive esophageal carcinoma." in: The Journal of clinical investigation, Vol. 102, Issue 4, pp. 821-7, 1998 (PubMed).