Interferon gamma Receptor beta Chain (IFNGR2) Antikörper

Antigen: Interferon gamma Receptor beta Chain (IFNGR2)

Synonyme: AF-1, IFGR2, IFNGT1

Klonalität: Polyklonal

Wirt: Maus

Reaktivität: Human

Applikation: Western Blot (WB), Durchflusszytometrie (FACS)

Produktnummer: ABIN361563

Produktbeschreibung

Weitere Bezeichnung: IFNGR2

Gen-ID: 3460

Immunogen: Recombinant protein of full length Human IFNGR2

Format: Affinity-purified

Beschreibung: Function: Part of the receptor for interferon gamma. Required for signal transduction. This accessory factor is an integral part of the IFN-gamma signal transduction pathway and is likely to interact with GAF, JAK1, and/or JAK2 Subcellular location: Membrane, Single-pass type I membrane protein Sequence similarities: Belongs to the type II cytokine receptor family. Contains 2 fibronectin type-III domains.

Anwendungen

Applikationshinweise: WB: 1ug/ml. FACS: 1ug/ml

Konzentration: 0.5 mg/ml

Reinigung: Protein A purified

Buffer: PBS, pH 7.2

Lagerung: Store below -20 degrees Celsius

Forschungsgebiet: Immunologie

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

IFNGR2 transfected 293T cell lysate

IFNGR2 expressing 293 cells 0. Negative control Transfectant

Publikationen

Publikationen: Soh, Donnelly, Kotenko et al.: "Identification and sequence of an accessory factor required for activation of the human interferon gamma receptor." in: Cell, Vol. 76, Issue 5, pp. 793-802, 1994 (PubMed).

Rhee, Ebensperger, Dembic et al.: "The structure of the gene for the second chain of the human interferon-gamma receptor." in: The Journal of biological chemistry, Vol. 271, Issue 46, pp. 28947-52, 1997 (PubMed).

Gerhard, Wagner, Feingold et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004 (PubMed).