Regulator of G-Protein Signalling 7 (RGS7) Antikörper

Antigen: Regulator of G-Protein Signalling 7 (RGS7)

Synonyme: RGS7, dRGS7, DmelCG9108, CG9108, MGC137820, zgc:92793, LOC100230842

Klonalität: Polyklonal

Wirt: Maus

Reaktivität: Human, Ratte (Rattus)

Applikation: Western Blot (WB), Durchflusszytometrie (FACS)

Produktnummer: ABIN361562

Produktbeschreibung

Weitere Bezeichnung: RGS7

Gen-ID: 6000

Immunogen: Recombinant protein of full length Human RGS7

Format: Affinity-purified

Beschreibung: Function: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactiveGDP-bound form. Activity on G(o)-alpha is specifically enhanced by the RGS6/GNG5 dimer. May play a role in synaptic vesicle exocytosis.May play important role in the rapid regulation of neuronal excitability and the cellular responses to short-lived stimulations Sequence similarities: Contains 1 DEP domain. Contains 1 G protein gamma domain. Contains 1 RGS domain.

Anwendungen

Applikationshinweise: WB: 1ug/ml. FACS: 1ug/ml

Konzentration: 0.5 mg/ml

Reinigung: Protein A purified

Buffer: PBS, pH 7.2

Lagerung: Store below -20 degrees Celsius

Forschungsgebiet: Signaltransduktion

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

rat brain tissue lysate RGS7 transfected 293T cell lysate

rat brain tissue lysate RGS7 transfected 293T cell lysate

RGS7 expressing 293 cells. Negative control Transfectant

Publikationen

Publikationen: Koelle, Horvitz: "EGL-10 regulates G protein signaling in the C. elegans nervous system and shares a conserved domain with many mammalian proteins." in: Cell, Vol. 84, Issue 1, pp. 115-25, 1996 (PubMed).

Kim, Arnould, Sellin et al.: "Interaction between RGS7 and polycystin." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 11, pp. 6371-6, 1999 (PubMed).

Snow, Betts, Mangion et al.: "Fidelity of G protein beta-subunit association by the G protein gamma-subunit-like domains of RGS6, RGS7, and RGS11." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 11, pp. 6489-94, 1999 (PubMed).