HLA Class I Histocompatibility Antigen, alpha Chain E (HLAE) Antikörper

Antigen: HLA Class I Histocompatibility Antigen, alpha Chain E (HLAE)

Synonyme: MHC, QA1, EA1.2, EA2.1, HLA-6.2, DKFZp686P19218

Klonalität: Polyklonal

Wirt: Maus

Reaktivität: Human

Applikation: Western Blot (WB), Durchflusszytometrie (FACS)

Produktnummer: ABIN361560

Produktbeschreibung

Weitere Bezeichnung: HLA-E

Gen-ID: 3133

Immunogen: Recombinant protein of full length Human HLA-E

Format: Affinity-purified

Beschreibung: Function: Preferably binds to a peptide derived from the signal sequence of most HLA-A, -B, -C and -G molecules Subcellular location: Membrane, Single-pass type I membrane protein Polymorphism The following alleles of E-1 are known: E*0101, E*0102, E*0103 and E*0104. The sequence shown is that of E*0101 Sequence similarities: Belongs to the MHC class I family. Contains 1 Ig-like C1-type (immunoglobulin-like) domain.

Anwendungen

Applikationshinweise: WB: 1ug/ml. FACS: 1ug/ml

Konzentration: 0.5 mg/ml

Reinigung: Protein A purified

Buffer: PBS, pH 7.2

Lagerung: Store below -20 degrees Celsius

Forschungsgebiet: Immunologie

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

human spleen tissue lysate HLA-E transfected 293T cell lysate

human spleen tissue lysate HLA-E transfected 293T cell lysate

HLA-E expressing 293 cells. Negative control Transfectant

Publikationen

Publikationen: Mizuno, Trapani, Koller et al.: "Isolation and nucleotide sequence of a cDNA clone encoding a novel HLA class I gene." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 140, Issue 11, pp. 4024-30, 1988 (PubMed).

Ulbrecht, Couturier, Martinozzi et al.: "Cell surface expression of HLA-E: interaction with human beta2-microglobulin and allelic differences." in: European journal of immunology, Vol. 29, Issue 2, pp. 537-47, 1999 (PubMed).

Gerhard, Wagner, Feingold et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004 (PubMed).