Sphingosine-1-Phosphate Receptor 4 (S1PR4) Antikörper

Antigen: Sphingosine-1-Phosphate Receptor 4 (S1PR4)

Synonyme: EDG3, LPB3, S1P3, EDG-3, FLJ37523, FLJ93220, MGC71696, EDG6, LPC1, S1P4, SLP4, Edg6, lpC1, MGC129298, S1PR4, edg6

Klonalität: Polyklonal

Wirt: Maus

Reaktivität: Human

Applikation: Western Blot (WB)

Produktnummer: ABIN361550

Produktbeschreibung

Weitere Bezeichnung: EDG6

Gen-ID: 8698

Immunogen: Recombinant protein of full length Human EDG6

Format: Affinity-purified

Beschreibung: Function: Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diversephysiological effect on most types of cells and tissues. May be involved in cell migration processes that are specific for lymphocytes Subcellular location: Cell membrane, Multi-pass membrane protein Tissue specificity: Specifically expressed in fetal and adult lymphoid and hematopoietic tissue as well as in lung. Considerable level ofexpression in adult and fetal spleen as well as adult peripheral leukocytes and lung. Lower expression in adult thymus, lymph node, bonemarrow, and appendix as well as in fetal liver, thymus, and lung Sequence similarities: Belongs to the G-protein coupled receptor 1 family.

Anwendungen

Applikationshinweise: WB: 1ug/ml.

Konzentration: 1 mg/ml

Reinigung: Protein A purified

Buffer: PBS, pH 7.2

Lagerung: Store below -20 degrees Celsius

Forschungsgebiet: Signaltransduktion

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

EDG6 transfected 293T cell lysate 0 0

EDG6 transfected 293T cell lysate 0 0

Publikationen

Publikationen: Graeler, Bernhardt, Lipp: "EDG6, a novel G-protein-coupled receptor related to receptors for bioactive lysophospholipids, is specifically expressed in lymphoid tissue." in: Genomics, Vol. 53, Issue 2, pp. 164-9, 1998 (PubMed).

Yamazaki, Kon, Sato et al.: "Edg-6 as a putative sphingosine 1-phosphate receptor coupling to Ca(2+) signaling pathway." in: Biochemical and biophysical research communications, Vol. 268, Issue 2, pp. 583-9, 2000 (PubMed).

Gerhard, Wagner, Feingold et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004 (PubMed).