SEMA4D/CD100 Antikörper

Produktnummer ABIN361535

Produktdetails anti-SEMA4D/CD100 Antikörper

Target: SEMA4D/CD100 (SEMA4D) (Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4D (SEMA4D))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SEMA4D/CD100 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP), ELISA

Aufreinigung: ProteinG Affinity Purified

Immunogen: Recombinant protein of Mouse Semaphorin 4D (extracellular domain)

Klon: SK-3

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: ELISA: 1-10ug/ml. IP: 5ug/ml. FACS: 0.05ug/ml

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.25 mg/ml

Buffer: PBS [containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat]

Konservierungsmittel: ProClin

Lagerung: -20 °C

Details zu SEMA4D/CD100

Target: SEMA4D/CD100 (SEMA4D) (Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4D (SEMA4D))

Andere Bezeichnung: Semaphorin 4D (SEMA4D Produkte)

Synonyme: C9orf164 antikoerper, CD100 antikoerper, M-sema-G antikoerper, SEMAJ antikoerper, coll-4 antikoerper, Semacl2 antikoerper, Semaj antikoerper, Semcl2 antikoerper, COLL-4 antikoerper, semaphorin 4D antikoerper, sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D antikoerper, Sema4d antikoerper, SEMA4D antikoerper

Hintergrund: Semaphorins are a family of phylogeneticallyconserved soluble and transmembrane proteins. Semaphorins were originally identified as axon guidance factors during neuronal development.Semaphorins are now known to be widely expressed mediators that play significantroles in immune responses and organ morphogenesis. Sema4D (also known as CD100) is a 150-kDa transmembrane protein of the class IV semaphorin subfamily. Sema4D is expressed at high levels in lymphoid organs, including the spleen, thymus, and lymph nodes, and in non-lymphoidorgans, such as the brain, heart, andkidney. In lymphoid organs, Sema4D is expressed abundantly by T cells but weakly by B cells. Its expression is significantly enhanced inboth T and B cells, following their respective activation. Sema4D is proteolyticallycleaved from their transmembrane form to generate 120-kDa soluble forms. Two types of receptors, Plexin-B1 and CD72, have been identified for soluble Sema4D.

Gen-ID: 20354

Pathways: Regulation of Cell Size