Neuropeptide FF Receptor 1 (NPFFR1) Antikörper

Antigen: Neuropeptide FF Receptor 1 (NPFFR1)

Synonyme: NPFF1, GPR147, NPFF1R1, OT7T022, FLJ10751, Gm236, Gpr147, RFRPR, MGC83178, NPFFR1, LOC100230250

Klonalität: Monoklonal (2A10)

Wirt: Maus

Reaktivität: Human, Ratte (Rattus)

Applikation: ELISA, Immunhistochemie (IHC)

Produktnummer: ABIN361533

Produktbeschreibung

Weitere Bezeichnung: NPFFR1

Gen-ID: 64106

Immunogen: Partial peptide of Human NPFFR1 (3rd extracellular domain)

Format: Affinity-purified

Isotyp: IgG1 kappa  (Passende Sekundärantikörper)

Klon: 2A10

Beschreibung: Function: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulatingpeptides.Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action byassociation with G proteins that activate a phosphatidylinositol-calcium second messenger system Sequence similarities: Belongs to the G-protein coupled receptor 1 family.

Anwendungen

Applikationshinweise: ELISA: 1.0ug/ml. IHC: 5-10ug/ml

Konzentration: 0.25 mg/ml

Reinigung: ProteinG Affinity Purified

Buffer: PBS [containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat]

Lagerung: Store below -20 degrees Celsius

Forschungsgebiet: Signaltransduktion

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Rat testis tissue

Publikationen

Publikationen: Gouardueres, Puget, Zajac: "Detailed distribution of neuropeptide FF receptors (NPFF1 and NPFF2) in the rat, mouse, octodon, rabbit, guinea pig, and marmoset monkey brains: a comparative autoradiographic study." in: Synapse (New York, N.Y.), Vol. 51, Issue 4, pp. 249-69, 2003 (PubMed).

Goncharuk, Zeng, Wang et al.: "Distribution of the neuropeptide FF1 receptor (hFF1) in the human hypothalamus and surrounding basal forebrain structures: immunohistochemical study." in: The Journal of comparative neurology, Vol. 474, Issue 4, pp. 487-503, 2004 (PubMed).