GABA Transporter 2 (GAT2) Antikörper

Antigen: GABA Transporter 2 (GAT2)

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Ratte (Rattus)

Applikation: Immunhistochemie (IHC)

Produktnummer: ABIN361451

Produktbeschreibung

Weitere Bezeichnung: GABA Transporter (GAT) 2

Format: Affinity-purified

Beschreibung: Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABAA receptor (GABAA-R) subtype. GABA plasma membrane transporters (GATs) influence synaptic neurotransmission by high-affinity uptake and release of GABA. To date, four distinct GABA transporters have been identified: GAT-1, GAT-2, GAT-3, and BGT-1. GAT-2 is found in a wide range of neuronal and non-neuronal cells including dendrites and axon terminals as well as epithelial cells and cells forming the pia and arachnoid complex (Conti et al., 1999).

Spezifität: Specific for the ~82k GAT-2 protein.

Anwendungen

Applikationshinweise: Recommended Dilution: IHC: 1:100-1:200 Quality Control: Immunohistochemistry performed on each lot.

Reinigung: Prepared from rabbit serum by affinity purification.

Lagerung: Store at -20 °C, stable for 1 year

Beschränkungen: Nur für Forschungszwecke einsetzbar