Phosphatidylethanolamine Binding Protein (PEBP) Antikörper

Antigen: Phosphatidylethanolamine Binding Protein (PEBP)

Synonyme: MGC56033, zgc:56033, zgc:76942, PEBP1, PBP, PEBP

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Ratte (Rattus)

Applikation: Western Blot (WB)

Produktnummer: ABIN361407

Produktbeschreibung

Weitere Bezeichnung: PEBP (Phosphatidylethanolamine Binding Protein)

Beschreibung: Phosphatidylethanolamine binding protein (PEBP), also known as Raf kinase inhibitory protein (RKIP) is a highly conserved multifunctional protein that modulates the Raf/MAPK signaling cascade and has been implicated as a suppressor of metastatic cancer (Trakul N et al., 2005). PEBP has been shown to not only inhibit cell proliferation but also to induce differentiation of human keratinocytes (Yamazaki et al., 2004). Dysregulation of calpain activity results in cellular degeneration in conditions such as Alzheimer?s disease and recently PEBP has been identified as a potential in vivo calpain substrate (Chen at al., 2006) Anti-PEBP Western blot of rat brain lysate showing the specific immunolabeling of the ~ 22k PEBP protein.

Spezifität: Specific for the ~ 22k PEBP protein in Western blots

Anwendungen

Applikationshinweise: Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.

Reinigung: Neat serum

Lagerung: Store at -20 °C, stable for 1 year

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Western blots of rat brain lysate showing the specific immunolabeling of the ~ 22k PEBP protein.