Calcium Channel, Voltage-Dependent, gamma Subunit 2 (CACNG2) Antikörper

Antigen: Calcium Channel, Voltage-Dependent, gamma Subunit 2 (CACNG2)

Synonyme: MGC138502, MGC138504, stg, wag, waggler, AW060990, MGC123981, stargazer, stargazin, B230105C07Rik, B930041E13Rik, Ipr328, CACNG2, MGC64200, zgc:64200

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Ratte (Rattus)

Applikation: Western Blot (WB)

Produktnummer: ABIN361402

Produktbeschreibung

Weitere Bezeichnung: Stargazin

Format: Affinity-purified

Beschreibung: Stargazin is a member of the transmembrane AMPAR regulatory proteins (TARP) family and is involved in glutamate receptor trafficking. It has been recently demonstrated (Tomita et al., 2005, Priel et al., 2005) that the interaction between stargazin and AMPA receptors is critical for the correct localization of the receptors at the synapse. Phosphorylation of the stargazin protein at Thr 321 by Protein Kinase A regulates its interaction with PSD-95 and synaptic targeting of AMPA receptors (Choi et al., 2002). Anti-Stargazin Western blot of rat synaptic membrane (SPM) showing specific immunolabeling of the ~ 36k stargazin protein.

Spezifität: Specific for the ~36k stargazin protein. Immunolabeling of the stargazin band is blocked by preadsorption with the peptide used as antigen.

Anwendungen

Applikationshinweise: Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.

Reinigung: Prepared from rabbit serum by affinity purification via chromatography on an affinity column to which the C-terminal peptide used as immunogen was coupled.

Lagerung: Store at -20 °C, stable for 1 year

Forschungsgebiet: Signaltransduktion

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Western blots of rat synaptic membrane (SPM) showing specific immunolabeling of the ~ 36k stargazin protein.