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Amyloid beta (A4) Precursor Protein (APP) Antikörper

Antigen

Amyloid beta (A4) Precursor Protein (APP)

Synonyme APP, APP-like, APPL, Abeta, BcDNA:GH04413, EG:65F1.5, DmelCG7727, CG7727, AAA, AD1, PN2, ABPP, APPI, CVAP, ABETA, CTFgamma, aaa, ad1, pn2, abpp, appi, cvap, abeta, MGC88882, ctfgamma
Klonalität Polyklonal
Wirt
Alternativen

Kaninchen

Reaktivität
Alternativen

Ratte (Rattus)

Applikation
Alternativen Western Blot (WB)
Produktnummer ABIN361390
Menge 100 µl  (Varianten)
Preis 311,54 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferbar innerhalb von 5 bis 7 Werktagen

Produktbeschreibung

Weitere Bezeichnung Amyloid Precursor Protein
Format Affinity-purified
Beschreibung A large body of evidence has implicated the amyloid precursor protein (APP) in the pathogenesis of Alzheimer's disease (AD) (Kamenetz et al., 2003). The phosphorylation of APP at Thr668 is thought to play a critical role in generation of the soluble APP (beta) and beta-amyloid peptide (abeta) which are the major components of senile plaques in patient brains inflicted with AD (Liu et al., 2003, Ando et al., 2001). Anti-Amyloid Precursor Protein Western blot of rat hippocampal lysate showing specific immunolabeling of the ~115k APP protein.
Spezifität Specific for ~115k APP protein. Immunolabeling of the APP protein band is completely blocked by preadsorption of the antibody with the peptide used as antigen.

Anwendungen

Applikationshinweise Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.
Reinigung Prepared from rabbit serum by affinity purification on a column made with the C-terminal peptide used as antigen.
Lagerung Store at -20 °C, stable for 1 year
Forschungsgebiet Neurologie, Alzheimer-Krankheit (Morbus Alzheimer)
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen

Alternativen zu Antigen "Amyloid beta (A4) Precursor Protein (APP)", Typ "Antikörper" finden
Wirte Kaninchen (165), Maus (67), Ziege (26)
Reaktivitäten Human (206), Maus (82), Ratte (Rattus) (60), Affe (8), Huhn (7), Hund (6), Rind (Kuh) (4), Schwein (3), Kaninchen (3), Meerschweinchen (2), Primate (2), Nerz (1)
Applikationen Western Blot (WB) (194), Immunhistochemie (Paraffinschnitte) (IHC (p)) (71), Enzyme Immunoassay (EIA) (53), ELISA (50), Immunfluoreszenz (IF) (30), Immunhistochemie (IHC) (28), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (20), Immunpräzipitation (IP) (20), Durchflusszytometrie (FACS) (12), Dot Blot (Dot) (6), Immunzytochemie (ICC) (3), Radioimmunoassay (RIA) (2)
Konjugate FITC (1)
Epitope C-Term (10), variant 1 (10), N-Term (5), p668 (5), pThr668 (4), AA 653-662 (3), AA 292-312 (2), AA 44-63 (2), AA 671-685 (2), AA 747-761 (2), Ab-730 (2), pSer198 (2), pSer730 (2), pTyr756 (2), AA 1-14 (1), AA 1-40 (1), AA 350-450 (1), C-Term D672 (1), Carboxyl Terminal amino acids 737-751 (1), Cerebral 1 (1), KPI Domain (1), Y756 (1), all isoforms (1), pS198 (1), pS730 (1), pThr743/668 (1)