Chromogranin-A Antikörper

Antigen: Chromogranin-A

Klonalität: Monoklonal (D11-4)

Wirt: Maus

Reaktivität: Human

Applikation: Western Blot (WB)

Produktnummer: ABIN361259

Produktbeschreibung

Produktmerkmale: Positive control: PC12.
Cellular Localization: Secretary protein

Swiss-Prot: P10645

Immunogen: This antibody is produced by immunizing mouse with a synthetic peptide (KLH-coupled) corresponding to near C-terminal residues of Chromogranin A.

Kreuzreaktivität: Human, Maus, Ratte (Rattus)

Format: Liquid

Isotyp: IgG2a  (Passende Sekundärantikörper)

Klon: D11-4

Beschreibung: Chromogranin A is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is located in secretory vesicles of neurons and endocrine cells. Chromogranin A is the precursor to several functional peptides including vasostatin, pancreastatin, catestatin and parastatin. These peptides negatively modulate the neuroendocrine function of the releasing cell (autocrine) or nearby cells (paracrine). Chromogranin A might promote the generation of secretory granules. It is used as an indicator for pancreas and prostate cancer. It might play a role in early neoplasic progression. It is also elevated in diabetes

Spezifität: Cellular Localization: Secretory protein. Molecular Weight: ~86kDa

Molekulargewicht: ~86kDa

Anwendungen

Applikationshinweise: WB: 1:2,000

Konzentration: 0.43mg/ml

Buffer: 1xTBS (pH7.4), 0.5%BSA, 25%Glycerol.

Konservierungsmittel: 0.05% Sodium Azide.

Lagerung: Store at +4° C after thawing. Aliquot store at -20° C or -80° C. Avoid repeated freeze / thaw cycles.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Western blot analysis on PC12 cell lysates using anti-Chromogranin A monoclonal antibody