CD44 (CD44) Antikörper

Antigen: CD44 (CD44)

Synonyme: IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1, CDW44, CSPG8, HCELL, MUTCH-I, ECMR-III, MGC10468

Klonalität: Monoklonal (A7-1)

Wirt: Maus

Reaktivität: Human

Applikation: Western Blot (WB)

Produktnummer: ABIN361251

Produktbeschreibung

Weitere Bezeichnung: CD44

Swiss-Prot: P16070

Immunogen: This antibody is produced by immunizing mouse with a synthetic peptide (KLH-coupled) corresponding to the residues of human CD44.

Format: Liquid

Klon: A7-1

Beschreibung: CD44 is a cell-surface glycoprotein postulated to play a role in a variety of biological processes, including lymphocyte homing and tumor-cell metastasis. It mediates cell-cell and cell-matrix interactions through its affinity for hyaluronic acid (HA), and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. CD44 is highly polymorphic, possesses a number of alternative splice variants and undergoes extensive post-translational modifications

Spezifität: Cellular Localization: cytoplasmic membrane. Molecular Weight: 80-250kDa

Anwendungen

Applikationshinweise: Recommended Dilutions: WB: 1:500-1:1000. Positive Control: Hela cells

Konzentration: 0.5mg/ml

Reinigung: Immunogen affinity purified

Buffer: 1*TBS (pH7.4), 0.5%BSA, 25%Glycerol. Preservative: 0.05% Sodium Azide.

Lagerung: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Forschungsgebiet: Stammzellen, Hämopoetische Vorläufer, CD Antigene, Oberflächenrezeptoren der Immunzellen , Krebs, Zellzyklus

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Western blot analysis on Hela using anti-CD44 monoclonal antibody. CD44