Tissue Factor Pathway Inhibitor 2 (TFPI2) Antikörper

Antigen: Tissue Factor Pathway Inhibitor 2 (TFPI2)

Synonyme: PP5, REF1, TFPI-2, FLJ21164, AV000670, PP5/TFPI-2, TFPI2, MGC68843, MGC108301, si:ch211-262k23.2, tfpi2

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Western Blot (WB), Immunhistochemie (Paraffinschnitte) (IHC (p))

Produktnummer: ABIN361212

Produktbeschreibung

Weitere Bezeichnung: Tissue factor pathway inhibitor 2, TFPI2

Immunogen: A synthetic peptide corresponding to a sequence at the Middle region of human TFPI2, identical to the related rat and mouse sequence

Format: Affinity-purified

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: Tissue factor pathway inhibitor 2, also known as TFPI2, is a human gene which is located at 7q22. It is an important regulator of the extrinsic pathway of blood coagulation through its ability to inhibit factor Xa and factor VIIa-tissue factor activity. After a 22-residue signal peptide, the mature TFPI2 protein contains 213 amino acids with 18 cysteines and 2 canonical N-linked glycosylation sites. The purified recombinant TFPI2 strongly inhibited the amidolytic activities of trypsin and the factor VIIa-tissue factor complex. 1 The latter inhibition was markedly enhanced in the presence of heparin. Mouse TFPI2 mRNA is highly expressed in developing mouse placenta, as in human. 2 And there are also high transcript levels in adult mouse liver and kidney.

Anwendungen

Applikationshinweise: Recommended Dilutions: WB 1ug/ml. IHC-P 2ug/ml. Antigen Retrieval By Heat

Reinigung: Immunogen affinity purified.

Buffer: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na 2 HPO 4 , 0.05mg Thimerosal, 0.05mg NaN 3 .

Lagerung: Reconstitution: 0.2ml of distilled water will yield a concentration of 500ug/ml. At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for longer time.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Human mammary cancer

anti-Tissue Factor Pathway Inhibitor 2 (TFPI2) antibody (Image 2)