Sodium Channel, Voltage-Gated, Type I, beta (SCN1B) Antikörper

Antigen: Sodium Channel, Voltage-Gated, Type I, beta (SCN1B)

Synonyme: GEFSP1

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human, Ratte (Rattus), Maus

Applikation: Western Blot (WB)

Produktnummer: ABIN361210

Produktbeschreibung

Weitere Bezeichnung: Sodium channel, voltage-gated, beta 1, SCN1B

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminal of human SCN1B, identical to the related rat and mouse sequence

Format: Affinity-purified

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: Voltage-gated sodium (Na+) channels are essential for the generation and propagation of action potentials in striated muscle and neuronal tissues. The complete coding region of Sodium channel, voltage-gated, beta 1(SCN1B) is found in approximately 9.0 kb of genomic DNA and consists of five exons (72 to 749 bp) and four introns (90 bp to 5.5 kb). It is mapped to 19q13.1 and can act as a candidate gene for hereditary disorders affecting membrane excitability. 1 Sodium channel beta1 subunits play important roles in the regulation of sodium channel density and localization and are involved in axo-glial communication at nodes of Ranvier. 2

Anwendungen

Applikationshinweise: Recommended Dilutions: WB 1ug/ml

Reinigung: Immunogen affinity purified.

Buffer: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na 2 HPO 4 , 0.05mg Thimerosal, 0.05mg NaN 3 .

Lagerung: Reconstitution: 0.2ml of distilled water will yield a concentration of 500ug/ml. At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for longer time.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

anti-Sodium Channel, Voltage-Gated, Type I, beta (SCN1B) antibody