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Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) Antikörper

Antigen

Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8)
Synonyme CAP4, MACH, MCH5, FLICE, ALPS2B, Casp-8, FLJ17672, MGC78473, Mch5, Caspase-8, MGC92075, caspase-8, zgc:92075, casp8-A, xCaspase-8, CASP8, casp8, DKFZp469A1428
Klonalität Polyklonal
Wirt
Alternativen

Kaninchen
Reaktivität
Alternativen

Human, Ratte (Rattus), Maus
Applikation
Alternativen Western Blot (WB)
Produktnummer ABIN361204
Menge 100ug  (Varianten)
Preis 217,95 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 5 bis 7 Werktagen

anti-Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) antibody

Produktbeschreibung
Anwendungen Bilder Alternativen Sekundärantikörper Varianten zurück nach oben

Weitere Bezeichnung Caspase-8 (P18)
Immunogen A synthetic peptide corresponding to a sequence at the middle region of human Caspase-8(P18), different to the related mouse sequence by a single amino acids
Format Affinity-purified
Isotyp IgG  (Passende Sekundärantikörper)
Beschreibung Caspase 8 is a caspase protein. It most likely acts upon caspase 3. This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. The human CASP8 gene, whose product is also known as caspase 8 and FLICE, encodes an interleukin-1beta converting enzyme (ICE)-related cysteine protease that is activated by the engagement of several different death receptors. Caspase 8 is immediately recruited to the Fas receptor once it oligomerizes, and its protease activity is crucial for the apoptotic response generated by the resulting death-inducing signaling complex (DISC). This gene contains at least 11 exons spanning approximately 30kb on human chromosome band 2q33-34. This region of human chromosome 2 was previously reported as the location of the CASP10 gene, whose product is closely related to caspase 8. 1 Caspase-8 deficiency in humans is compatible with normal development and shows that caspase-8 has a postnatal role in immune activation of naive lymphocytes. 2

Anwendungen
Bilder Alternativen Sekundärantikörper Varianten zurück nach oben

Applikationshinweise Recommended Dilutions: WB 1ug/ml
Reinigung Immunogen affinity purified.
Buffer Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na 2 HPO 4 , 0.05mg Thimerosal, 0.05mg NaN 3 .
Lagerung Reconstitution: 0.2ml of distilled water will yield a concentration of 500ug/ml. At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for longer time.
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen
Anwendungen Bilder Sekundärantikörper Varianten zurück nach oben

Alternativen zu Antigen "Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8)", Typ "Antikörper" finden
Wirte Kaninchen (87), Maus (36), Ratte (5), Huhn (1)
Reaktivitäten Human (115), Maus (50), Ratte (Rattus) (46), Rind (Kuh) (29), Hund (17), Huhn (16), Schwein (16), Affe (12), Schimpanse (2), Kaninchen (2), Pferd (1), Nerz (1)
Applikationen Western Blot (WB) (93), Immunhistochemie (Paraffinschnitte) (IHC (p)) (27), Durchflusszytometrie (FACS) (25), Immunfluoreszenz (IF) (23), Immunpräzipitation (IP) (23), ELISA (13), Enzyme Immunoassay (EIA) (11), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (10), Immunhistochemie (IHC) (8), Dot Blot (Dot) (3), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), ELISA (Fangantikörper) (1), Immunzytochemie (ICC) (1), Immunoelectron Microscopy (IEM) (1)
Konjugate Biotin (3), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
Epitope N-Term (8), C-Term (7), active (5), Cleaved-Asp384 (2), Ab-347 (1), Middle (1), active/cleaved (1), pSer347 (1), pTyr380 (1)